Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | FABP3 | P05413 | 9/20 | 0.45 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL887075 | 1.00 | CA1 (0.46) | CA1FABP3FFAR3HDAC3HDAC1 | |
| SCHEMBL1121644 | 1.00 | CA1 (0.46) | CA1FABP3FFAR3HDAC3HDAC1 | |
| SCHEMBL640842 | 0.98 | CA1 (0.44) | CA1FABP3FFAR3HDAC3HDAC1 | |
| SCHEMBL11011436 | 0.98 | CA1 (0.44) | CA1FABP3FFAR3HDAC3HDAC1 | |
| SCHEMBL5575143 | 0.98 | CA1 (0.44) | CA1FABP3FFAR3HDAC3HDAC1 | |
| SCHEMBL23174700 | 0.98 | CA1 (0.44) | CA1FABP3FFAR3HDAC3HDAC1 | |
| SCHEMBL10825634 | 0.98 | CA1 (0.44) | CA1FABP3FFAR3HDAC3HDAC1 | |
| SCHEMBL21384974 | 0.98 | CA1 (0.44) | CA1FABP3FFAR3HDAC3HDAC1 | |
| Silver SCHEMBL21899896 | 0.98 | CA1 (0.44) | CA1FABP3FFAR3HDAC3HDAC1 | |
| SCHEMBL22439765 | 0.98 | CA1 (0.44) | CA1FABP3FFAR3HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7533723-B2 | Well bore treatment fluid | SCHLUMBERGER TECHNOLOGY CORPORATION (US) | 2009-05-19 | — | — | US | disclosed |
| US-20070095534-A1 | Well bore treatment fluid | SCHLUMBERGER TECHNOLOGY CORPORATION | 2007-05-03 | — | — | US | disclosed |
| WO-2005035936-A1 | WELL BORE TREATMENT FLUID | SCHLUMBERGER TECHNOLOGY B.V. (NL) | 2005-04-21 | — | — | WO | disclosed |