SCHEMBL393157

SCHEMBL393157

CCC(=O)OC1=NCCO1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.33
HIF1A Q16665 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
RECQL P46063 1/20 0.33
KMT2A Q03164 1/20 0.33
ELANE P08246 1/20 0.31
KDM4E B2RXH2 1/20 0.30
NPC1 O15118 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
PKM P14618 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27795313 0.86 ALDH1A1 (0.38) KMT2AKDM4EALDH1A1
SCHEMBL28267678 0.85 HDAC3 (0.32) KMT2AKDM4EALDH1A1MAPT
SCHEMBL7456171 0.82 MGAM (0.38)
SCHEMBL21611098 0.80 DGKA (0.42) SMN1; SMN2KMT2A
SCHEMBL21611111 0.80 DGKA (0.42) SMN1; SMN2KMT2A
SCHEMBL8656142 0.79
SCHEMBL28275692 0.77 KDM4E (0.34) KDM4E
SCHEMBL28301898 0.77 KDM4E (0.34) KDM4E
SCHEMBL28170502 0.76 KDM4E (0.36) HIF1AKDM4EALDH1A1MAPT
SCHEMBL7930722 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11925689-B2 Multifunctional forms of polyoxazoline copolymers and drug compositions comprising the same SERINA THERAPEUTICS, INC. (US) 2024-03-12 US disclosed
US-20230009076-A1 POLYOXAZOLINE-DRUG CONJUGATES WITH NOVEL PHARMACOKINETIC PROPERTIES SERINA THERAPEUTICS, INC. (US) 2023-01-12 US disclosed
US-20220193243-A1 MULTIFUNCTIONAL FORMS OF POLYOXAZOLINE COPOLYMERS AND DRUG COMPOSITIONS COMPRISING THE SAME SERINA THERAPEUTICS, INC. (US) 2022-06-23 US disclosed
EP-3990026-A1 POLYOXAZOLINE-DRUG CONJUGATES WITH NOVEL PHARMACOKINETIC PROPERTIES Serina Therapeutics, Inc. (US) 2022-05-04 EP disclosed
CN-114258309-A Polyoxazoline-drug conjugates with novel pharmacokinetic properties 塞瑞纳治疗公司 2022-03-29 CN disclosed
US-11213588-B2 Multifunctional forms of polyoxazoline copolymers and drug compositions comprising the same SERINA THERAPEUTICS, INC. (US) 2022-01-04 US disclosed
WO-2020264505-A1 POLYOXAZOLINE-DRUG CONJUGATES WITH NOVEL PHARMACOKINETIC PROPERTIES SERINA THERAPEUTICS, INC. (US) 2020-12-30 WO disclosed
US-20190134208-A1 MULTIFUNCTIONAL FORMS OF POLYOXAZOLINE COPOLYMERS AND DRUG COMPOSITIONS COMPRISING THE SAME SERINA THERAPEUTICS (AL), INC. 2019-05-09 US disclosed
US-10166294-B2 Multifunctional forms of polyoxazoline copolymers and drug compositions comprising the same SERINA THERAPEUTICS, INC. (US) 2019-01-01 US disclosed
CN-108025196-A Water-In-Oil light screening composition with organic sunscreen actives 莱雅公司 2018-05-11 CN disclosed
EP-2235090-B1 MULTIFUNCTIONAL FORMS OF POLYOXAZOLINE COPOLYMERS AND DRUG COMPOSITIONS COMPRISING THE SAME SERINA THERAPEUTICS INC (US) 2013-09-04 EP disclosed
US-8501899-B2 Multifunctional forms of polyoxazoline copolymers and drug compositions comprising the same SERINA THERAPEUTICS, INC. (US) 2013-08-06 US disclosed
US-20120136123-A1 Multifunctional Forms of Polyoxazoline Copolymers and Drug Compositions Comprising the Same SERINA THERAPEUTICS, INC. (US) 2012-05-31 US disclosed
US-20120123055-A1 Multifunctional Forms of Polyoxazoline Copolymers and Drug Compositions Comprising the Same SERINA THERAPEUTICS, INC. (US) 2012-05-17 US disclosed
US-8110651-B2 Multifunctional forms of polyoxazoline copolymers and drug compositions comprising the same SERINA THERAPEUTICS, INC. (US) 2012-02-07 US disclosed
US-8101706-B2 Multifunctional forms of polyoxazoline copolymers and drug compositions comprising the same SERINA THERAPEUTICS, INC. (US) 2012-01-24 US disclosed
US-20110009594-A1 MULTIFUNCTIONAL FORMS OF POLYOXAZOLINE COPOLYMERS AND DRUG COMPOSITIONS COMPRISING THE SAME SERINA THERAPEUTICS, INC. (US) 2011-01-13 US disclosed
US-20100330023-A1 Multifunctional Forms of Polyoxazoline Copolymers and Drug Compositions Comprising the Same SERINA THERAPEUTICS, INC. (US) 2010-12-30 US disclosed
EP-2235090-A2 MULTIFUNCTIONAL FORMS OF POLYOXAZOLINE COPOLYMERS AND DRUG COMPOSITIONS COMPRISING THE SAME Serina Therapeutics, Inc. (US) 2010-10-06 EP disclosed
WO-2009089542-A2 MULTIFUNCTIONAL FORMS OF POLYOXAZOLINE COPOLYMERS AND DRUG COMPOSITIONS COMPRISING THE SAME SERINA THERAPEUTICS, INC. (US) 2009-07-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220193243-A1 MULTIFUNCTIONAL FORMS OF POLYOXAZOLINE COPOLYMERS AND DRUG COMPOSITIONS COMPRISING THE SAME ERBB3, ERBB2, PANK2 ESR1 3533/4885HIF1A 2673/4885SMN1; SMN2 2101/4885
US-20100330023-A1 Multifunctional Forms of Polyoxazoline Copolymers and Drug Compositions Comprising the Same ERBB3, ERBB2, PANK2 ESR1 3533/4885HIF1A 2673/4885SMN1; SMN2 2101/4885
US-20230009076-A1 POLYOXAZOLINE-DRUG CONJUGATES WITH NOVEL PHARMACOKINETIC PROPERTIES CYP3A5, CYP2C19, CYP3A7 ESR1 4157/4885HIF1A 4332/4885SMN1; SMN2 2938/4885
US-10166294-B2 Multifunctional forms of polyoxazoline copolymers and drug compositions comprising the same ERBB3, ERBB2, PANK2 ESR1 3533/4885HIF1A 2673/4885SMN1; SMN2 2101/4885
US-20190134208-A1 MULTIFUNCTIONAL FORMS OF POLYOXAZOLINE COPOLYMERS AND DRUG COMPOSITIONS COMPRISING THE SAME ERBB3, ERBB2, PANK2 ESR1 3533/4885HIF1A 2673/4885SMN1; SMN2 2101/4885
US-11925689-B2 Multifunctional forms of polyoxazoline copolymers and drug compositions comprising the same ERBB3, ERBB2, PANK2 ESR1 3533/4885HIF1A 2673/4885SMN1; SMN2 2101/4885
US-11213588-B2 Multifunctional forms of polyoxazoline copolymers and drug compositions comprising the same ERBB3, ERBB2, PANK2 ESR1 3533/4885HIF1A 2673/4885SMN1; SMN2 2101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.