Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.83 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | INSR | P06213 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | TEK | Q02763 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3939849 | 0.92 | FAAH (0.98) | FAAHGRM4TRPV1PIK3C3KDM2B | |
| SCHEMBL3936930 | 0.91 | FAAH (1.00) | FAAHTRPV1PIK3C3KDM2BIGF1R | |
| SCHEMBL3933967 | 0.89 | FAAH (0.83) | FAAHIGF1R | |
| SCHEMBL4019524 | 0.86 | FAAH (0.78) | FAAHKDM2B | |
| SCHEMBL3929528 | 0.83 | FAAH (0.85) | FAAHTRPV1HTR6HTR7IGF1R | |
| SCHEMBL4014996 | 0.82 | FAAH (0.70) | FAAH | |
| SCHEMBL3936220 | 0.81 | FAAH (1.00) | FAAH | |
| SCHEMBL3933752 | 0.81 | FAAH (0.89) | FAAH | |
| SCHEMBL4012669 | 0.81 | FAAH (0.79) | FAAHTRPV1HTR6HTR7IGF1R | |
| SCHEMBL3937880 | 0.81 | FAAH (0.74) | FAAHGRM4TRPV1HTR6HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |