Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.70 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4019524 | 0.88 | FAAH (0.78) | FAAHTHRBGAAKDM4E | |
| SCHEMBL3939849 | 0.84 | FAAH (0.98) | FAAH | |
| SCHEMBL3936930 | 0.83 | FAAH (1.00) | FAAHKDM4E | |
| SCHEMBL3933967 | 0.82 | FAAH (0.83) | FAAHKDM4E | |
| SCHEMBL3932151 | 0.82 | FAAH (0.83) | FAAH | |
| SCHEMBL3937880 | 0.79 | FAAH (0.74) | FAAH | |
| SCHEMBL3929528 | 0.77 | FAAH (0.85) | FAAHDRD2 | |
| SCHEMBL4012669 | 0.76 | FAAH (0.79) | FAAH | |
| SCHEMBL3939141 | 0.75 | FAAH (0.74) | FAAHPRMT5WDR77 | |
| SCHEMBL4012253 | 0.75 | FAAH (0.68) | FAAHKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |