Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 3/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL95975 | 0.76 | KDM4E (0.65) | MLYCDPDE10ANAMPTHTTKDM4E | |
| SCHEMBL27594794 | 0.74 | SLC6A2 (0.42) | MLYCDALDH1A1CA12CA9SLC6A2 | |
| SCHEMBL5543209 | 0.74 | MLYCD (0.62) | MLYCDALDH1A1EGFRERBB2TSHR | |
| SCHEMBL18455023 | 0.73 | EGFR (0.46) | MLYCDALDH1A1ADRB2EGFRERBB2 | |
| SCHEMBL8016233 | 0.73 | MLYCD (0.40) | MLYCDALDH1A1KMT2AEGFRERBB2 | |
| SCHEMBL9001626 | 0.73 | ADRA2C (0.65) | MLYCDHTTALDH1A1ADRB2KMT2A | |
| SCHEMBL2960979 | 0.72 | USP2 (0.58) | HTTALDH1A1KDM4EKMT2ATSHR | |
| SCHEMBL8013240 | 0.71 | ADRA2C (0.55) | MLYCDPDE10AALDH1A1ADRB2ADRA2C | |
| SCHEMBL1928093 | 0.71 | PKM (0.54) | MLYCDHTTALDH1A1ADRB2KMT2A | |
| SCHEMBL9540613 | 0.71 | MLYCD (0.57) | MLYCDNAMPTALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2043644-A1 | NF- B INHIBITOR | Otsuka Pharmaceutical Co., Ltd. (JP) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008010601-A1 | NF- ϰB INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-01-24 | — | — | WO | disclosed |