Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 0.68 |
| ▸ | ALPL | P05186 | 9/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3929062 | 0.92 | FAAH (0.75) | FAAHALPLLMNASMN1; SMN2 | |
| SCHEMBL3931235 | 0.91 | FAAH (0.69) | FAAHALPLLMNASMN1; SMN2 | |
| SCHEMBL3931635 | 0.91 | FAAH (0.71) | FAAHALPLLMNASMN1; SMN2GAA | |
| SCHEMBL3942242 | 0.86 | FAAH (0.77) | FAAHLMNASMN1; SMN2 | |
| SCHEMBL3933839 | 0.85 | FAAH (0.86) | FAAHALPLLMNASMN1; SMN2 | |
| SCHEMBL3938565 | 0.85 | FAAH (0.77) | FAAHALPLLMNA | |
| SCHEMBL3939610 | 0.85 | FAAH (0.74) | FAAHALPLLMNASMN1; SMN2GAA | |
| SCHEMBL4017908 | 0.84 | FAAH (0.72) | FAAHSMN1; SMN2 | |
| SCHEMBL3939389 | 0.84 | FAAH (0.83) | FAAHLMNASMN1; SMN2 | |
| SCHEMBL4018033 | 0.84 | FAAH (0.65) | FAAHALPLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |