SCHEMBL3933081

SCHEMBL3933081

CC1(C)OC[C@H]2O[C@@H](OCC[Si](C)(C)C)[C@H](N)[C@@H](O)[C@@H]2O1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ YWHAZ P63104 3/20 0.32
▸ CA1 P00915 2/20 0.32
▸ CA2 P00918 2/20 0.32
▸ CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14330425 0.89 YWHAZ (0.36) YWHAZCA1CA2CA9
SCHEMBL14330424 0.86 YWHAZ (0.35) YWHAZCA1CA2CA9
SCHEMBL14330423 0.84 YWHAZ (0.34) YWHAZCA1CA2CA9
SCHEMBL15258385 0.81 CD209 (0.33) YWHAZ
SCHEMBL16135491 0.81 CD209 (0.33) YWHAZ
SCHEMBL7143326 0.81 YWHAZ (0.32) YWHAZCA1CA2CA9
SCHEMBL8582014 0.81 YWHAZ (0.32) YWHAZCA1CA2CA9
SCHEMBL16135486 0.80 CA2 (0.36) YWHAZCA1CA2CA9
SCHEMBL8435871 0.80 CA2 (0.36) YWHAZCA1CA2CA9
SCHEMBL12444536 0.78 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7541020-B2 Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors CORIXA CORPORATION (US) 2009-06-02 — — US disclosed
US-7063967-B2 Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors CORIXA CORPORATION (US) 2006-06-20 — — US disclosed
EP-0983286-B1 AMINOALKYL GLUCOSAMINE PHOSPHATE COMPOUNDS AND THEIR USE AS ADJUVANTS AND IMMUNOEFFECTORS CORIXA CORP (US) 2004-07-28 — — EP disclosed
US-6764840-B2 AUGMENT ANTIBODY PRODUCTION IN IMMUNIZED ANIMALS AS WELL AS STIMULATE CYTOKINE PRODUCTION AND ACTIVATE MACROPHAGES. CORIXA CORPORATION 2004-07-20 — — US disclosed
EP-1105401-B1 PHOSPHOGLYCOLIPID AND METHODS FOR ITS USE CORIXA CORP (US) 2004-04-07 — — EP disclosed
US-20030199460-A1 Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors CORIXA CORPORATION (US) 2003-10-23 — — US disclosed
US-20030092643-A1 Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors CORIXA CORPORATION 2003-05-15 — — US disclosed
EP-1230250-A2 AMINOALKYL GLUCOSAMINIDE PHOSPHATE COMPOUNDS AND THEIR USE AS ADJUVANTS AND IMMUNOEFFECTORS CORIXA CORPORATION (US) 2002-08-14 — — EP disclosed
US-20020048588-A1 Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors CORIXA CORPORATION 2002-04-25 — — US disclosed
US-6355257-B1 Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors CORIXA CORPORATION 2002-03-12 — — US disclosed
US-20020013291-A1 Phosphoglycolipid and methods for its use CORIXA CORPORATION 2002-01-31 — — US disclosed
US-6303347-B1 VACCINES CORIXA CORPORATION 2001-10-16 — — US disclosed
EP-1105401-A1 PHOSPHOGLYCOLIPID AND METHODS FOR ITS USE CORIXA CORPORATION (US) 2001-06-13 — — EP disclosed
WO-2001034617-A2 AMINOALKYL GLUCOSAMINIDE PHOSPHATE COMPOUNDS AND THEIR USE AS ADJUVANTS AND IMMUNOEFFECTORS CORIXA CORPORATION (US) 2001-05-17 — — WO disclosed
US-6113918-A IMMUNOLOGY RIBI IMMUNOCHEM RESEARCH, INC. (US) 2000-09-05 — — US disclosed
EP-0983286-A1 AMINOALKYL GLUCOSAMINE PHOSPHATE COMPOUNDS AND THEIR USE AS ADJUVANTS AND IMMUNOEFFECTORS CORIXA CORPORATION (US) 2000-03-08 — — EP disclosed
WO-2000011010-A1 PHOSPHOGLYCOLIPID AND METHODS FOR ITS USE CORIXA CORPORATION (US) 2000-03-02 — — WO disclosed
US-6013640-A ANTIISCHEMIC AGENTS RIBI IMMUNOCHEM RESEARCH, INC. (US) 2000-01-11 — — US disclosed
WO-1998050399-A1 AMINOALKYL GLUCOSAMINE PHOSPHATE COMPOUNDS AND THEIR USE AS ADJUVANTS AND IMMUNOEFFECTORS CORIXA CORPORATION (US) 1998-11-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030199460-A1 Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors DNPEP, CD68, MGAT3 YWHAZ 3155/4885CA1 2470/4885CA2 1273/4885
US-20020048588-A1 Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors DNPEP, CD68, MGAT3 YWHAZ 3221/4885CA1 2584/4885CA2 1308/4885
US-20030092643-A1 Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors DNPEP, CD68, MGAT3 YWHAZ 3155/4885CA1 2470/4885CA2 1273/4885
US-20020013291-A1 Phosphoglycolipid and methods for its use PYGL, GPI, PNLIP YWHAZ 2685/4885CA1 1016/4885CA2 1662/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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