SCHEMBL393344

SCHEMBL393344

O=C=Nc1ccccc1-c1cccc(Cl)c1N=C=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.44
GABRA1 P14867 1/20 0.42
GABRB2 P47870 1/20 0.42
HTR3E A5X5Y0 1/20 0.35
HTR3B O95264 1/20 0.35
HTR3A P46098 1/20 0.35
HTR3D Q70Z44 1/20 0.35
HTR3C Q8WXA8 1/20 0.35
MAPK1 P28482 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
GALR3 O60755 1/20 0.34
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP2A6 P11509 1/20 0.31
MAPT P10636 3/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3635498 0.89 GABRA1 (0.50) CYP3A4GABRA1GABRB2MAPK1TDP1
SCHEMBL17847486 0.85 CYP3A4 (0.45) CYP3A4GABRA1GABRB2HTR3EHTR3B
SCHEMBL9183951 0.85 CYP3A4 (0.50) CYP3A4GABRA1GABRB2TDP1ALDH1A1
SCHEMBL462306 0.83 CYP3A4 (0.52) CYP3A4GABRA1GABRB2HTR3EHTR3B
SCHEMBL6318550 0.83 CYP3A4 (0.38) CYP3A4GABRA1GABRB2HTR3EHTR3B
SCHEMBL112824 0.81 CYP3A4 (0.56) CYP3A4GABRA1GABRB2MAPK1TDP1
SCHEMBL11770819 0.80 CYP3A4 (0.42) CYP3A4GABRA1GABRB2HTR3EHTR3B
SCHEMBL6866459 0.79 CYP3A4 (0.53) CYP3A4GABRA1GABRB2MAPK1TDP1
SCHEMBL29099802 0.79 CYP3A4 (0.54) CYP3A4GABRA1GABRB2MAPK1TDP1
SCHEMBL326586 0.79 GABRA1 (0.56) CYP3A4GABRA1GABRB2HTR3EHTR3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 519 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5401782-A Storage stable epoxy resin of bisphenol A half blocked with isocyanate and sulfide forming sulfonium NIPPON PAINT CO., LTD. (JP) 1995-03-28 US claimed
EP-0416762-B1 Cationic electrodeposition paint composition NISSAN MOTOR (JP) 1994-06-15 EP claimed
US-5164430-A ACRYLIC, URETHANATED EPOXY AND PARTICULATE AMINE-EPOXY/POLYBUTADIENE CATIONIC RESINS NISSAN MOTOR CO., LTD. (JP) 1992-11-17 US claimed
EP-0416762-A1 Cationic electrodeposition paint composition NISSAN MOTOR CO., LTD. (JP) 1991-03-13 EP claimed
CN-118139904-A Aqueous silicone acrylic resin system and coating SWIMC有限公司 2024-06-04 CN disclosed
CN-113785024-B Polymer composition for thin coatings SWIMC有限公司 2023-08-15 CN disclosed
WO-2023049793-A1 WATERBORNE SILICONE ACRYLIC RESIN SYSTEMS AND COATINGS SWIMC LLC (US) 2023-03-30 WO disclosed
US-20220228025-A1 POLYMER COMPOSITION FOR THIN COATINGS SWIMC LLC 2022-07-21 US disclosed
CN-113785024-A Polymer composition for thin coatings SWIMC有限公司 2021-12-10 CN disclosed
US-10928728-B2 Photoactivable nitrogen bases BASF SE (DE) 2021-02-23 US disclosed
US-20210033972-A1 PHOTOACTIVABLE NITROGEN BASES BASF SE (DE) 2021-02-04 US disclosed
WO-2020247727-A1 POLYMER COMPOSITION FOR THIN COATINGS SWIMC LLC (US) 2020-12-10 WO disclosed
US-4007154-A Novel pigment paste for cationic electrodeposition PPG INDUSTRIES, INC. (US) 1977-02-08 US disclosed
US-3984299-A A BLOCKED ORGANIC POLYISOCYANATE AND A PRIMARY OR SECONDARY AMINE-POLYEPOXIDE ADDUCT PPG INDUSTRIES, INC. (US) 1976-10-05 US disclosed
US-3975250-A Electrodeposition with reactive modifier for amine group-containing, acid-solubilized resins PPG INDUSTRIES, INC. (US) 1976-08-17 US disclosed
US-3959106-A EPOXY COMPOUNDS; SULFIDES PPG INDUSTRIES, INC. (US) 1976-05-25 US disclosed
US-3953391-A ALKYLENEIMINE-MODIFIED ACRYLIC COPOLYMERSACID PPG INDUSTRIES, INC. (US) 1976-04-27 US disclosed
US-3947339-A Method of electrodepositing primary amine group-containing cationic resins PPG INDUSTRIES, INC. (US) 1976-03-30 US disclosed
US-3947338-A Method of electrodepositing self-crosslinking cationic compositions PPG INDUSTRIES, INC. (US) 1976-03-30 US disclosed
US-3935087-A Method for electrodeposition of self-crosslinking cationic compositions PPG INDUSTRIES, INC. (US) 1976-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210033972-A1 PHOTOACTIVABLE NITROGEN BASES CBR1, ARNT, NR0B1 CYP3A4 180/4885GABRA1 532/4885GABRB2 726/4885
US-10928728-B2 Photoactivable nitrogen bases CBR1, NR0B1, NR0B2 CYP3A4 259/4885GABRA1 557/4885GABRB2 680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.