⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11983441 | 0.74 | INMT (0.41) | — | |
| SCHEMBL6299340 | 0.73 | — | — | |
| SCHEMBL11758314 | 0.73 | — | — | |
| SCHEMBL15330621 | 0.73 | — | — | |
| SCHEMBL12862581 | 0.71 | PIK3CD (0.47) | — | |
| SCHEMBL15330853 | 0.70 | INMT (0.34) | — | |
| SCHEMBL8775918 | 0.69 | MGLL (0.43) | — | |
| SCHEMBL12635490 | 0.68 | GSK3B (0.45) | — | |
| SCHEMBL9514131 | 0.67 | ALDH1A1 (0.60) | — | |
| SCHEMBL3965014 | 0.67 | MAPT (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041128-A2 | SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS | Allergan, Inc. (US) | 2009-04-01 | — | — | EP | disclosed |
| WO-2007146856-A2 | SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS | ALLERGAN, INC. (US) | 2007-12-21 | — | — | WO | disclosed |