Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | INMT | O95050 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28626171 | 0.98 | MGLL (0.46) | MGLLFAAHGBA1ALOX5PTGS1 | |
| SCHEMBL4974886 | 0.94 | MEN1 (0.39) | MGLLFAAHGBA1INMTALDH1A1 | |
| SCHEMBL4975560 | 0.86 | — | — | |
| SCHEMBL14580451 | 0.81 | INMT (0.54) | MGLLFAAHINMTALDH1A1MAPT | |
| SCHEMBL27345851 | 0.81 | ALDH1A1 (0.42) | INMTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL10978172 | 0.81 | ALDH1A1 (0.31) | INMTALDH1A1 | |
| SCHEMBL9698433 | 0.80 | MGLL (0.44) | MGLLFAAHGBA1ALOX5PTGS1 | |
| SCHEMBL4079827 | 0.78 | KEAP1 (0.32) | INMTSMN1; SMN2 | |
| SCHEMBL167690 | 0.77 | ALDH1A1 (0.42) | MGLLFAAHGBA1ALOX5ALDH1A1 | |
| SCHEMBL1499885 | 0.77 | MGLL (0.37) | MGLLFAAHGBA1ALOX5PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114634506-B | Substituted 1H-indol-2-one-yl-3, 5-substituted aryl-1, 3-thiazolidinedione derivatives | 复旦大学 | 2024-04-19 | — | — | CN | claimed |
| CN-114634506-A | Substituted 1H-indol-2-one-link-3, 5-substituted aryl-1, 3-thiazolidinone derivatives | 复旦大学 | 2022-06-17 | — | — | CN | claimed |
| CN-110950809-B | Synthetic post-treatment method of aryl triazolinone compound | 北京颖泰嘉和生物科技股份有限公司 | 2021-07-27 | — | — | CN | claimed |
| CN-110950809-A | Synthetic post-treatment method of aryl triazolinone compound | 北京颖泰嘉和生物科技股份有限公司 | 2020-04-03 | — | — | CN | claimed |
| EP-0640076-B1 | TRIAZOLINONE RING FORMATION IN TERT-BUTANOL | FMC CORP (US) | 1997-11-26 | — | — | EP | claimed |
| JP-2592774-B2 | — | — | 1997-03-19 | — | — | JP | claimed |
| EP-0490936-B1 | PRODUCTION OF TRIAZOLINONES | FMC CORP (US) | 1996-10-23 | — | — | EP | claimed |
| US-5440045-A | Triazolinone ring formation in tert-butanol | FMC CORPORATION (US) | 1995-08-08 | — | — | US | claimed |
| EP-0640076-A4 | TRIAZOLINONE RING FORMATION IN TERT-BUTANOL. | FMC CORP (US) | 1995-04-12 | — | — | EP | claimed |
| EP-0640076-A1 | TRIAZOLINONE RING FORMATION IN TERT-BUTANOL | FMC CORPORATION (US) | 1995-03-01 | — | — | EP | claimed |
| WO-1993023382-A1 | TRIAZOLINONE RING FORMATION IN TERT-BUTANOL | FMC CORPORATION (US) | 1993-11-25 | — | — | WO | claimed |
| US-5256793-A | Triazolinone ring formation in tert-butanol | FMC CORPORATION (US) | 1993-10-26 | — | — | US | claimed |
| EP-0490936-A4 | PRODUCTION OF TRIAZOLINONES | — | 1992-10-14 | — | — | EP | claimed |
| EP-0490936-A1 | PRODUCTION OF TRIAZOLINONES. | FMC CORP (US) | 1992-06-24 | — | — | EP | claimed |
| WO-1991003470-A1 | PRODUCTION OF TRIAZOLINONES | FMC CORPORATION (US) | 1991-03-21 | — | — | WO | claimed |
| US-4980480-A | Production of triazolinones | FMC CORPORATION (US) | 1990-12-25 | — | — | US | claimed |
| EP-3802530-B1 | HETEROCYCLIC COMPOUNDS AS CLASS II PHOSPHOINOSITIDE 3-KINASE INHIBITORS | FORSCHUNGSVERBUND BERLIN EV (DE) | 2024-05-29 | — | — | EP | disclosed |
| CN-114634506-B | Substituted 1H-indol-2-one-yl-3, 5-substituted aryl-1, 3-thiazolidinedione derivatives | 复旦大学 | 2024-04-19 | — | — | CN | disclosed |
| US-4980480-A | Production of triazolinones | FMC CORPORATION (US) | 1990-12-25 | — | — | US | disclosed |
| EP-0011693-A1 | N-trifluoromethane-sulfonylaminophenyl-substituted N-heterocycles, their preparation, compositions containing them and their use in regulating plant growth | CIBA-GEIGY AG (CH) | 1980-06-11 | — | — | EP | disclosed |