Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 0.67 |
| ▸ | IGF1R | P08069 | 3/20 | 0.42 |
| ▸ | ALPL | P05186 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | FABP1 | P07148 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3930696 | 0.91 | FAAH (0.72) | FAAHALPLLMNASMN1; SMN2TP53 | |
| SCHEMBL3941391 | 0.91 | FAAH (0.77) | FAAHLMNAFABP1 | |
| SCHEMBL3943232 | 0.90 | FAAH (0.78) | FAAHIGF1RLMNASMN1; SMN2MKNK1 | |
| SCHEMBL3932778 | 0.90 | FAAH (0.70) | FAAHALPLLMNAMKNK1FABP1 | |
| SCHEMBL3941303 | 0.89 | FAAH (0.82) | FAAHIGF1RALPLMKNK1 | |
| SCHEMBL3929062 | 0.88 | FAAH (0.75) | FAAHALPLLMNASMN1; SMN2 | |
| SCHEMBL3931235 | 0.88 | FAAH (0.69) | FAAHALPLLMNASMN1; SMN2 | |
| SCHEMBL3942417 | 0.87 | FAAH (0.78) | FAAHIGF1RALPLMKNK1 | |
| SCHEMBL4014998 | 0.85 | FAAH (0.70) | FAAHALPLSMN1; SMN2MAPT | |
| SCHEMBL3931443 | 0.84 | FAAH (0.77) | FAAHIGF1RALPLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |