Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 0.70 |
| ▸ | FNTA | P49354 | 2/20 | 0.43 |
| ▸ | FNTB | P49356 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3929062 | 0.88 | FAAH (0.75) | FAAHALPLSMN1; SMN2 | |
| SCHEMBL4012470 | 0.88 | FAAH (0.78) | FAAHHSD17B10ALDH1A1EPHX2ALPL | |
| SCHEMBL4011830 | 0.87 | FAAH (0.65) | FAAHHSD17B10ALDH1A1EPHX2ALPL | |
| SCHEMBL3931443 | 0.87 | FAAH (0.77) | FAAHALDH1A1EPHX2ALPLKDM4E | |
| SCHEMBL3936894 | 0.87 | FAAH (0.79) | FAAHALDH1A1EPHX2ALPLKDM4E | |
| SCHEMBL4007889 | 0.85 | FAAH (0.67) | FAAHHSD17B10ALDH1A1EPHX2ALPL | |
| SCHEMBL4016142 | 0.85 | FAAH (0.67) | FAAHHSD17B10ALDH1A1EPHX2ALPL | |
| SCHEMBL3933996 | 0.85 | FAAH (0.67) | FAAHALPLMAPTSMN1; SMN2 | |
| SCHEMBL4018033 | 0.85 | FAAH (0.65) | FAAHHSD17B10ALDH1A1EPHX2ALPL | |
| SCHEMBL3934364 | 0.85 | FAAH (0.77) | FAAHFNTAFNTBALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |