Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 0.78 |
| ▸ | MKNK1 | Q9BUB5 | 5/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3941303 | 0.98 | FAAH (0.82) | FAAHMKNK1IGF1RPKM | |
| SCHEMBL3942417 | 0.95 | FAAH (0.78) | FAAHMKNK1IGF1RPKM | |
| SCHEMBL3936263 | 0.92 | FAAH (0.90) | FAAHMEN1KMT2ASMN1; SMN2GBA1 | |
| SCHEMBL3933996 | 0.90 | FAAH (0.67) | FAAHMKNK1IGF1RSMN1; SMN2MAPT | |
| SCHEMBL3932545 | 0.89 | FAAH (0.79) | FAAHMKNK1IGF1RMAPTTP53 | |
| SCHEMBL3931396 | 0.89 | FAAH (0.85) | FAAHMKNK1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL3933101 | 0.89 | FAAH (0.73) | FAAHMKNK1IGF1R | |
| SCHEMBL3942587 | 0.89 | FAAH (0.78) | FAAHMKNK1KMT2ALMNA | |
| SCHEMBL3930701 | 0.88 | FAAH (0.86) | FAAHMKNK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3941343 | 0.88 | FAAH (0.86) | FAAHMEN1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |