Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 3/20 | 0.67 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.67 |
| ▸ | CYP21A2 | P08686 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 3/20 | 0.56 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17599097 | 0.82 | CYP17A1 (0.55) | CYP17A1CYP11B1CYP21A2CYP3A4BAZ2B | |
| SCHEMBL17923079 | 0.82 | CYP17A1 (0.81) | CYP17A1CYP11B1CYP21A2CYP3A4 | |
| SCHEMBL17974024 | 0.82 | CYP17A1 (1.00) | CYP17A1CYP11B1CYP21A2CYP3A4MAPT | |
| SCHEMBL17923078 | 0.82 | CYP17A1 (0.81) | CYP17A1CYP11B1CYP21A2CYP3A4 | |
| SCHEMBL28474424 | 0.81 | CYP17A1 (0.54) | CYP17A1CYP11B1CYP21A2CYP3A4BAZ2B | |
| SCHEMBL2876802 | 0.81 | GPR119 (0.66) | CYP17A1CYP11B1CYP21A2CYP3A4BAZ2B | |
| SCHEMBL3934637 | 0.80 | CYP3A4 (0.52) | CYP17A1CYP11B1CYP21A2CYP3A4BAZ2B | |
| SCHEMBL10511405 | 0.80 | HRH4 (0.56) | CYP3A4BAZ2BGFERMAPTMEN1 | |
| SCHEMBL11072227 | 0.80 | ENPP2 (0.79) | CYP17A1CYP11B1CYP21A2CYP3A4BAZ2B | |
| SCHEMBL6603738 | 0.79 | CYP2C9 (0.73) | CYP17A1CYP11B1CYP21A2CYP3A4GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306055-A1 | PHENYLAZOLE COMPOUNDS, PRODUCTION PROCESS AND ANTIOXIDANTS | NIPPON SODA CO., LTD. (JP) | 2009-12-10 | — | — | US | disclosed |
| US-20090306055-A1 | PHENYLAZOLE COMPOUNDS, PRODUCTION PROCESS AND ANTIOXIDANTS | NIPPON SODA CO., LTD. (JP) | 2009-12-10 | — | — | US | disclosed |
| US-20090306055-A1 | PHENYLAZOLE COMPOUNDS, PRODUCTION PROCESS AND ANTIOXIDANTS | NIPPON SODA CO., LTD. (JP) | 2009-12-10 | — | — | US | disclosed |
| US-7553837-B2 | Phenylazole compounds production process and antioxidants | NIPPON SODA CO., LTD. (JP) | 2009-06-30 | — | — | US | disclosed |
| US-7553837-B2 | Phenylazole compounds production process and antioxidants | NIPPON SODA CO., LTD. (JP) | 2009-06-30 | — | — | US | disclosed |
| US-7553837-B2 | Phenylazole compounds production process and antioxidants | NIPPON SODA CO., LTD. (JP) | 2009-06-30 | — | — | US | disclosed |
| US-20060247228-A1 | Phenylazole compounds production process and antioxidants | NIPPON SODA CO., LTD. (JP) | 2006-11-02 | — | — | US | disclosed |
| EP-1650206-A1 | PHENYLAZOLE COMPOUNDS, PRODUCTION PROCESS, AND ANTIOXIDANTS | NIPPON SODA CO., LTD. (JP) | 2006-04-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306055-A1 | PHENYLAZOLE COMPOUNDS, PRODUCTION PROCESS AND ANTIOXIDANTS | NOX1, CBR1, AOX1 | CYP17A1 1844/4885CYP11B1 20/4885CYP21A2 822/4885 |
| US-20060247228-A1 | Phenylazole compounds production process and antioxidants | CBR1, CBR3, NOX3 | CYP17A1 1962/4885CYP11B1 16/4885CYP21A2 831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.