Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.55 |
| ▸ | HTR6 | P50406 | 5/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | KRAS | P01116 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14016155 | 0.84 | HTR2C (0.61) | HTR6HTR2AHTR2CHTR1DNOS3 | |
| Hydrochloric Acid SCHEMBL4664326 | 0.83 | HTR2C (0.59) | HTR6HTR2AHTR2CHTR1DNOS3 | |
| SCHEMBL30408910 | 0.82 | SCN9A (0.55) | SCN9AHTR6HTR2AHTR2CPLG | |
| SCHEMBL4007913 | 0.82 | SCN9A (0.55) | SCN9AHTR6HTR2AHTR2CPLG | |
| SCHEMBL21245721 | 0.79 | TUBB4A (0.43) | HTR2AHTR2CMTNR1AMTNR1BKRAS | |
| SCHEMBL2036331 | 0.78 | HTR2A (0.70) | SCN9AHTR6HTR2AHTR2CHTR1D | |
| SCHEMBL4007951 | 0.76 | HTR6 (0.51) | SCN9AHTR6PLGPLAUKRAS | |
| SCHEMBL30410682 | 0.76 | HTR6 (0.51) | SCN9AHTR6PLGPLAUKRAS | |
| SCHEMBL256348 | 0.76 | PLG (0.44) | HTR6HTR2AHTR2CPLGPLAU | |
| SCHEMBL7256513 | 0.73 | HTR7 (0.51) | SCN9AHTR6HTR2AHTR2CHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046789-A2 | LABELLED ANALOGUES OF HALOBENZAMIDES AS RADIOPHARMACEUTICALS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008012782-A2 | LABELLED ANALOGUES OF HALOBENZAMIDES AS RADIOPHARMACEUTICALS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2008-01-31 | — | — | WO | disclosed |