Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 1/20 | 0.45 |
| ▸ | GPR183 | P32249 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3934180 | 0.81 | TDP1 (0.38) | KMT2A | |
| SCHEMBL3945177 | 0.80 | MAPT (0.49) | MEN1KMT2A | |
| SCHEMBL2902830 | 0.78 | GPR183 (0.67) | F2RGPR183MEN1KMT2A | |
| SCHEMBL10300778 | 0.78 | GPR183 (0.67) | F2RGPR183MEN1KMT2A | |
| SCHEMBL1399050 | 0.78 | GPR183 (0.60) | F2RGPR183 | |
| SCHEMBL1399048 | 0.78 | GPR183 (0.60) | F2RGPR183 | |
| SCHEMBL3944887 | 0.78 | ALDH1A1 (0.45) | MEN1KMT2A | |
| SCHEMBL3935485 | 0.77 | ALDH1A1 (0.54) | F2RMEN1KMT2A | |
| SCHEMBL3944112 | 0.77 | ALDH1A1 (0.47) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9051982 | 0.74 | SIGMAR1 (0.62) | MEN1KMT2AATMFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046748-A1 | PHENYLPENTADIENOYL DERIVATIVES AND THEIR USE AS PAR 1 ANTAGONISTS | Pierre Fabre Medicament (FR) | 2009-04-15 | — | — | EP | claimed |
| WO-2007147822-A1 | PHENYLPENTADIENOYL DERIVATIVES AND THEIR USE AS PAR 1 ANTAGONISTS | PIERRE FABRE MEDICAMENT (FR) | 2007-12-27 | — | — | WO | claimed |