SCHEMBL393543

SCHEMBL393543

CCOC(=O)CNCC(=O)OCC.Fc1cccc(-c2nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.46
TRPM8 Q7Z2W7 2/20 0.43
ALDH1A1 P00352 5/20 0.41
PRNP P04156 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CSNK1D P48730 1/20 0.41
MAPT P10636 4/20 0.41
TP53 P04637 1/20 0.41
HPGD P15428 3/20 0.39
HTT P42858 2/20 0.39
LMNA P02545 2/20 0.39
HSD17B10 Q99714 1/20 0.39
JAK2 O60674 1/20 0.39
JAK3 P52333 1/20 0.39
NPC1 O15118 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
POLB P06746 1/20 0.38
MEN1 O00255 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL394049 0.88 MAPT (0.48) KDM4ETRPM8ALDH1A1MAPTHTT
SCHEMBL388857 0.87 ALDH1A1 (0.43) KDM4EALDH1A1TDP1MAPTTP53
SCHEMBL391281 0.86 ALDH1A1 (0.48) KDM4EALDH1A1PRNPTDP1MAPT
Urethane SCHEMBL4535005 0.85 CSNK1D (0.45) KDM4ETRPM8ALDH1A1PRNPTDP1
SCHEMBL391448 0.80 LMNA (0.43) ALDH1A1MAPTTP53HPGDLMNA
SCHEMBL391288 0.78 LMNA (0.41) KDM4EALDH1A1MAPTTP53HPGD
SCHEMBL391755 0.78 MAPK1 (0.38) KDM4EALDH1A1PRNPTDP1MAPT
SCHEMBL27951135 0.77 CASP1 (0.47) KDM4EALDH1A1MAPTTP53HPGD
SCHEMBL388905 0.77 HTT (0.44) ALDH1A1MAPTTP53HPGDHTT
SCHEMBL388673 0.77 PPID (0.40) ALDH1A1PRNPMAPTHPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240016965-A1 ULTRAVIOLET-SENSING MEMBER AND ULTRAVIOLET-SENSING KIT FUJIFILM CORPORATION (JP) 2024-01-18 US disclosed
WO-2022209858-A1 UV RADIATION SENSING MEMBER AND UV RADIATION SENSING KIT 富士フイルム株式会社 2022-10-06 WO disclosed
US-10591816-B2 Photosensitive resin composition, color filter, and liquid crystal display element thereof CHI MEI CORPORATION (TW) 2020-03-17 US disclosed
US-9939568-B2 Photosensitive resin composition for color filter and application of the same CHI MEI CORPORATION (TW) 2018-04-10 US disclosed
US-20180004086-A1 NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, PRODUCTION METHOD OF SPACER, PRODUCTION METHOD OF PROTECTION FILM, AND LIQUID CRYSTAL DISPLAY DEVICE CHI MEI CORPORATION (TW) 2018-01-04 US disclosed
US-9791773-B2 Photosensitive resin composition, color filter and liquid crystal display device CHI MEI CORPORATION (TW) 2017-10-17 US disclosed
US-20170235224-A1 PHOTOSENSITIVE RESIN COMPOSITION, COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT THEREOF CHI MEI CORPORATION (TW) 2017-08-17 US disclosed
US-9606436-B2 Photosensitive resin composition and application thereof CHI MEI CORPORATION (TW) 2017-03-28 US disclosed
US-20170052446-A1 PHOTOSENSITIVE RESIN COMPOSITION AND APPLICATION THEREOF CHI MEI CORPORATION (TW) 2017-02-23 US disclosed
US-9557443-B2 Photosensitive resin composition, black matrix, color filter, and liquid crystal display device CHI MEI CORPORATION (TW) 2017-01-31 US disclosed
US-20030229163-A1 Dye-containing curable composition, color filter prepared using the same, and process of preparing color filter FUJI PHOTO FILM CO., LTD. 2003-12-11 US disclosed
US-6191184-B1 SUITABLE FOR FORMATION OF LIQUID CRYSTAL DISPLAY (LCD) SPACERS OR PROTECTIVE LAYERS; PHOTOSETTING PROPERTIES ADHESIVENESS TO SUBSTRATES; MECHANICAL CHARACTERISTICS, STORAGE STABILITY SHOW EXCELLENT WORKING FUJI PHOTO FILM CO., LTD. (JP) 2001-02-20 US disclosed
US-6140016-A LIGHT SENSITIVE ELEMENTS AND COLOR FILTERS FUJI PHOTO FILM CO. LTD. (JP) 2000-10-31 US disclosed
US-6100312-A A CURABLE QUATERNARY AMMONIUM ADDITION COPOLYMER WITH A DISPERSED FINE-GRAIN PIGMENT; STORAGE STABILITY; COLOR FILTER USED IN A LIQUID CRYSTAL DISPLAY ELEMENT FUJI PHOTO CO., LTD. (JP) 2000-08-08 US disclosed
US-5998091-A COPOLYMER OF A MONOFUNCTIONAL MACROMONOMER HAVING A PARTICULAR POLYMERIZABLE DOUBLE BOND-CONTAINING GROUP SITUATED AT ONLY ONE END OF THE MAIN CHAIN, A QUATERNARY AMMONIUM SALT AND AN AMIDE FUJI PHOTO FILM CO., LTD. (JP) 1999-12-07 US disclosed
EP-0683434-B1 Photo-polymerizable composition, and image forming method and color filter using the composition FUJI PHOTO FILM CO LTD (JP) 1998-12-02 EP disclosed
EP-0683434-A1 Photo-polymerizable composition, and image forming method and color filter using the composition FUJI PHOTO FILM CO., LTD. (JP) 1995-11-22 EP disclosed
EP-0320264-B1 Colour filter MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 1994-04-27 EP disclosed
US-4934791-A PHOTOSENSITIVE ACRYLATE MONOMER, PIGMENTS, A BINDER AND A PHOTOPOLYMERIZATION INITIATOR MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1990-06-19 US disclosed
EP-0320264-A2 Colour filter MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1989-06-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240016965-A1 ULTRAVIOLET-SENSING MEMBER AND ULTRAVIOLET-SENSING KIT KIT, SARS1, UNG KDM4E 869/4885TRPM8 290/4885ALDH1A1 1641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.