Urethane

Urethane

SCHEMBL4535005

CCOC(N)=O.Fc1cccc(-c2nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n2)c1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK1D P48730 1/20 0.45
TRPM8 Q7Z2W7 4/20 0.45
MAPT P10636 2/20 0.41
TP53 P04637 1/20 0.41
JAK2 O60674 2/20 0.41
JAK3 P52333 1/20 0.41
ALDH1A1 P00352 4/20 0.39
HPGD P15428 3/20 0.39
MEN1 O00255 2/20 0.39
GAA P10253 2/20 0.39
KMT2A Q03164 2/20 0.39
PRNP P04156 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
LMNA P02545 3/20 0.39
KDM4E B2RXH2 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PKM P14618 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urethane SCHEMBL4538739 0.87 PDE4B (0.47) TRPM8MAPTJAK2JAK3ALDH1A1
Urethane SCHEMBL4530068 0.86 FOS (0.40) MAPTTP53ALDH1A1HPGDMEN1
SCHEMBL393543 0.85 KDM4E (0.46) CSNK1DTRPM8MAPTTP53JAK2
SCHEMBL9873206 0.79 TP53 (0.48) MAPTTP53ALDH1A1HPGDLMNA
SCHEMBL391755 0.76 MAPK1 (0.38) MAPTTP53ALDH1A1HPGDMEN1
Urethane SCHEMBL4535413 0.74 KDM4E (0.40) MAPTTP53ALDH1A1HPGDMEN1
SCHEMBL9874488 0.74 TTR (0.47) MAPTTP53ALDH1A1MEN1GAA
SCHEMBL9874485 0.74 TTR (0.47) MAPTTP53ALDH1A1MEN1GAA
SCHEMBL394049 0.73 MAPT (0.48) TRPM8MAPTALDH1A1LMNAKDM4E
SCHEMBL394307 0.73 XPO1 (0.37) TRPM8XPO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7575837-B2 Colored curable composition, color filter and method for producing the same FUJIFILM CORPORATION (JP) 2009-08-18 US disclosed
US-20060257762-A1 Colored curable composition, color filter and method for producing the same FUJI PHOTO FILM CO., LTD. 2006-11-16 US disclosed