Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MPI | P34949 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5546538 | 0.89 | ADH1B (0.50) | HTTSMN1; SMN2MEN1KMT2ATAAR1 | |
| SCHEMBL5544616 | 0.87 | ADH1B (0.48) | HTTSMN1; SMN2MEN1KMT2AATM | |
| SCHEMBL5993038 | 0.79 | P2RX7 (0.44) | HTTNPSR1KDM4EMAPK1P2RX7 | |
| SCHEMBL10133722 | 0.77 | LMNA (0.64) | NPSR1KDM4EALDH1A1L3MBTL1TP53 | |
| Formic Acid SCHEMBL5073763 | 0.77 | HTT (0.56) | HTTSMN1; SMN2MEN1KMT2AATM | |
| SCHEMBL2200019 | 0.76 | TAAR1 (0.61) | HTTSMN1; SMN2MEN1KMT2AATM | |
| SCHEMBL2221552 | 0.76 | MEN1 (0.67) | HTTSMN1; SMN2MEN1KMT2AATM | |
| SCHEMBL1460113 | 0.76 | TAAR1 (0.55) | HTTSMN1; SMN2MEN1KMT2AATM | |
| SCHEMBL15076833 | 0.76 | TAAR1 (0.60) | HTTSMN1; SMN2MEN1KMT2AATM | |
| SCHEMBL29569478 | 0.76 | TAAR1 (0.55) | HTTSMN1; SMN2MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |
| US-4423219-A | 6-/2-CHLORO-6-FLUOROBENZYL/AMINO-4-METHYLAMINO-5 -PHENYLAZOPYRIMIDINE, ANTIPROTOZOA | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-12-27 | — | — | US | disclosed |
| EP-0052959-A1 | Production of purine derivatives and intermediates therefor | Takeda Chemical Industries, Ltd. (JP) | 1982-06-02 | — | — | EP | disclosed |