Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3929837 | 0.83 | MAPK1 (0.40) | KMT2AKDM4EMAPK1SMN1; SMN2HPGD | |
| SCHEMBL3936587 | 0.80 | MAPK1 (0.48) | KMT2AMEN1BRCA1KDM4EMAPK1 | |
| SCHEMBL2393871 | 0.72 | CYP1A2 (0.47) | KMT2AMEN1KDM4EMAPK1ALDH1A1 | |
| SCHEMBL25164663 | 0.71 | NOS3 (0.42) | — | |
| SCHEMBL3936853 | 0.71 | POLB (0.50) | KMT2AKDM4ESMN1; SMN2L3MBTL1POLB | |
| SCHEMBL3884465 | 0.71 | CYP4F2 (0.48) | KMT2AMEN1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL31190874 | 0.70 | CYP1A2 (0.41) | KDM4EALDH1A1SMN1; SMN2HPGDCYP4F2 | |
| SCHEMBL3928245 | 0.69 | CYP1A2 (0.44) | MAPK1SMN1; SMN2L3MBTL1NPSR1CYP4F2 | |
| SCHEMBL3924887 | 0.68 | AGBL2 (0.55) | KMT2AMEN1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7447762 | 0.68 | MAPK1 (0.49) | KMT2AMEN1BRCA1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |