Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.58 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | AHR | P35869 | 1/20 | 0.58 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.58 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.58 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.58 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.58 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.58 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3943238 | 0.85 | KDM4E (0.55) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL31457901 | 0.81 | CTSV (0.58) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL1162107 | 0.81 | CTSV (0.58) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL19211138 | 0.80 | KDM4E (0.54) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL3935995 | 0.79 | KDM4E (0.57) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL19211147 | 0.77 | CTSV (0.58) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL1161271 | 0.77 | CTSV (0.58) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL49270 | 0.77 | LOXL2 (0.56) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL31716577 | 0.77 | CTSV (0.58) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL4764681 | 0.77 | CTSV (0.67) | KDM4EALDH1A1GAAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100196476-A1 | PROCESS FOR THE PREPARATION AND PHARMACEUTICAL FORMULATIONS FOR 4-QUINOLINONES AND QUINOLINES AND USE THEREOF | FUNDACAO UNIVERSIDADE FEDERAL DE SAO CARLOS (BR) | 2010-08-05 | — | — | US | disclosed |
| EP-2167468-A2 | PROCESS FOR THE PREPARATION AND PHARMACEUTICAL FORMULATIONS FOR 4-QUINOLINONES AND QUINOLINES AND USE THEREOF | Fundação Universidade Federal De São Carlos (BR) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008144865-A2 | PROCESS FOR THE PREPARATION AND PHARMACEUTICAL FORMULATIONS FOR 4-QUINOLINONES AND QUINOLINES AND USE THEREOF | FUNDAÇÃO UNIVERSIDADE FEDERAL DE SÃO CARLOS (BR) | 2008-12-04 | — | — | WO | disclosed |
| CN-1414951-A | Drug discharge pump inhibitor | FUNDAMENTAL THERAPEUTICAL INC (US) | 2003-04-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100196476-A1 | PROCESS FOR THE PREPARATION AND PHARMACEUTICAL FORMULATIONS FOR 4-QUINOLINONES AND QUINOLINES AND USE THEREOF | PF4, KCNQ1, KCNQ2 | KDM4E 599/4885ALDH1A1 2185/4885GAA 1634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.