Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.82 |
| ▸ | FAAH | O00519 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | GFER | P55789 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14417613 | 1.00 | SMN1; SMN2 (0.82) | SMN1; SMN2FAAHALDH1A1MEN1MAPT | |
| SCHEMBL4075701 | 1.00 | SMN1; SMN2 (0.82) | SMN1; SMN2FAAHALDH1A1MEN1MAPT | |
| SCHEMBL945536 | 0.90 | SMN1; SMN2 (1.00) | SMN1; SMN2FAAHALDH1A1MEN1MAPT | |
| SCHEMBL945534 | 0.90 | SMN1; SMN2 (1.00) | SMN1; SMN2FAAHALDH1A1MEN1MAPT | |
| SCHEMBL393998 | 0.85 | FAAH (0.78) | SMN1; SMN2FAAHALDH1A1MEN1MAPT | |
| SCHEMBL393675 | 0.83 | FAAH (1.00) | SMN1; SMN2FAAHALDH1A1MEN1MAPT | |
| SCHEMBL395724 | 0.80 | FAAH (0.76) | SMN1; SMN2FAAHALDH1A1MEN1MAPT | |
| SCHEMBL395281 | 0.79 | FAAH (0.83) | SMN1; SMN2FAAHALDH1A1MEN1MAPT | |
| SCHEMBL393680 | 0.79 | FAAH (0.83) | SMN1; SMN2FAAHALDH1A1MEN1MAPT | |
| SCHEMBL393500 | 0.79 | MAPT (0.81) | SMN1; SMN2FAAHALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070207093-A1 | Hydrazone derivatives and uses thereof | LINQUAGEN CORP. | 2007-09-06 | — | — | US | claimed |
| EP-1951215-A4 | HYDRAZONE DERIVATIVES AND USES THEREOF | REDPOINT BIO CORP (US) | 2009-07-29 | — | — | EP | disclosed |
| EP-1951215-A2 | HYDRAZONE DERIVATIVES AND USES THEREOF | Redpoint Bio Corporation (US) | 2008-08-06 | — | — | EP | disclosed |
| US-20070207093-A1 | Hydrazone derivatives and uses thereof | LINQUAGEN CORP. | 2007-09-06 | — | — | US | disclosed |
| WO-2007056159-A2 | HYDRAZONE DERIVATIVES AND USES THEREOF | REDPOINT BIO CORPORATION (US) | 2007-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070207093-A1 | Hydrazone derivatives and uses thereof | TAS2R1, TAS2R5, TAS1R1 | SMN1; SMN2 4734/4885FAAH 2368/4885ALDH1A1 72/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.