Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CBS | P35520 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28636154 | 0.91 | MAPT (0.39) | MAOAMAOBALDH1A1CBSCYP19A1 | |
| SCHEMBL20550365 | 0.79 | MAOA (0.45) | MAOAMAOBMMP2MMP3MMP9 | |
| SCHEMBL28636824 | 0.74 | MIF (0.41) | MAOAMAOBALDH1A1CYP19A1MEN1 | |
| SCHEMBL30543094 | 0.73 | CYP19A1 (0.46) | MAOBALDH1A1CBSCYP19A1CYP1A1 | |
| SCHEMBL6498085 | 0.72 | PTPN1 (0.48) | MAOBALDH1A1CYP19A1CYP3A4CYP1A1 | |
| SCHEMBL29099779 | 0.72 | PTPN1 (0.48) | MAOAMAOBALDH1A1CYP19A1CYP3A4 | |
| SCHEMBL29358153 | 0.72 | ALDH1A1 (0.41) | MAOAMAOBMMP2MMP3MMP9 | |
| SCHEMBL911922 | 0.71 | ALDH1A1 (0.44) | MAOAMAOBALDH1A1CYP19A1CYP3A4 | |
| SCHEMBL29462263 | 0.70 | MET (0.45) | MAOAMAOBMMP2MMP3MMP9 | |
| SCHEMBL29360007 | 0.69 | ALDH1A1 (0.57) | ALDH1A1CYP19A1CYP3A4CYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1630160-B1 | THE ISOFLAVONE DERIVATIVES OF TECTORIDIN, THE PREPARATION THEREOF AND THE ANTI-VIRUS MEDICINES CONTAINING THE SAME AS THE EFFECTIVE CONSTITUENTS | CHENGDU DIKANG PHARMACEUTICAL (CN) | 2009-04-08 | — | — | EP | claimed |