Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | TTR | P02766 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | SLCO2B1 | O94956 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20550365 | 0.79 | MAOA (0.45) | ALDH1A1MAOAMAOBPTPN1CYP19A1 | |
| SCHEMBL29462263 | 0.75 | MET (0.45) | ALDH1A1MAOAMAOBPTPN1CYP19A1 | |
| SCHEMBL571667 | 0.73 | CYP19A1 (0.41) | ALDH1A1MAOAMAOBPTPN1CYP19A1 | |
| SCHEMBL3937086 | 0.71 | MAOA (0.41) | ALDH1A1MAOAMAOBCYP19A1CYP3A4 | |
| SCHEMBL1428288 | 0.71 | ALDH1A1 (0.53) | ALDH1A1MAOAMAOBPTPN1CYP19A1 | |
| SCHEMBL29993584 | 0.70 | ALDH1A1 (0.37) | ALDH1A1MAOAMAOBPTPN1CYP3A4 | |
| SCHEMBL28636154 | 0.70 | MAPT (0.39) | ALDH1A1MAOAMAOBCYP19A1CYP3A4 | |
| SCHEMBL8572826 | 0.68 | CYP19A1 (0.37) | ALDH1A1MAOAMAOBCYP19A1CYP3A4 | |
| SCHEMBL8575536 | 0.68 | CYP19A1 (0.37) | ALDH1A1MAOAMAOBCYP19A1CYP3A4 | |
| SCHEMBL3182940 | 0.68 | MAOA (0.54) | ALDH1A1MAOAMAOBPTPN1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7867993-B2 | Preparation containing oxidized flavonoid derivatives | MERCK PATENT GMBH (DE) | 2011-01-11 | — | — | US | disclosed |
| US-20080319050-A1 | Preparation Containing Oxidized Flavonoid Derivatives | MERCK PATENT GMBH (DE) | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080319050-A1 | Preparation Containing Oxidized Flavonoid Derivatives | NQO1, LPO, NDUFV2 | ALDH1A1 339/4885MAOA 59/4885MAOB 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.