Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6573723 | 0.82 | FFAR1 (0.52) | FFAR1LMNALOXL2NPY5RTDP1 | |
| SCHEMBL10520154 | 0.81 | CYP19A1 (0.42) | HDAC6SMN1; SMN2NPC1RAB9A | |
| SCHEMBL925108 | 0.81 | KEAP1 (0.55) | FFAR1TDP1HDAC2HDAC8HDAC6 | |
| SCHEMBL3940845 | 0.79 | FFAR1 (0.51) | FFAR1LMNA | |
| SCHEMBL17967141 | 0.79 | PLAAT3 (0.45) | FFAR1HDAC2HDAC8HDAC6 | |
| SCHEMBL5644564 | 0.78 | FFAR1 (0.48) | FFAR1HDAC8 | |
| SCHEMBL28165994 | 0.77 | ALDH1A1 (0.44) | FFAR1TDP1 | |
| SCHEMBL7425058 | 0.77 | FFAR1 (0.47) | FFAR1LMNALOXL2NPY5RTDP1 | |
| SCHEMBL7178176 | 0.76 | IAPP (0.53) | FFAR1LMNALOXL2NPY5RTDP1 | |
| SCHEMBL3929597 | 0.75 | F2RL1 (0.68) | FFAR1TDP1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016410-A2 | CHEMICAL COMPOUNDS 831 | ASTRAZENECA AB (SE) | 2009-02-05 | — | — | WO | disclosed |