Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 6/20 | 0.69 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.67 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.56 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | CCR4 | P51679 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4762592 | 0.87 | MCHR1 (0.80) | DRD4MCHR1SIGMAR1SLC6A12SLC6A13 | |
| SCHEMBL9590523 | 0.85 | DRD4 (0.67) | DRD4CXCR3MCHR1SIGMAR1SLC6A12 | |
| SCHEMBL27430491 | 0.85 | SIGMAR1 (0.79) | DRD4CXCR3SIGMAR1 | |
| SCHEMBL3935469 | 0.83 | SIGMAR1 (0.67) | DRD4CXCR3MCHR1SIGMAR1HRH3 | |
| SCHEMBL3938952 | 0.83 | HRH3 (0.56) | DRD4CXCR3MCHR1SIGMAR1HRH3 | |
| SCHEMBL4305546 | 0.80 | L3MBTL1 (0.64) | DRD4CXCR3MCHR1SIGMAR1HRH3 | |
| SCHEMBL22233246 | 0.79 | SIGMAR1 (0.61) | DRD4CXCR3SIGMAR1 | |
| SCHEMBL3587801 | 0.79 | SIGMAR1 (0.61) | DRD4CXCR3SIGMAR1 | |
| SCHEMBL3938953 | 0.78 | CCR4 (0.58) | DRD4CXCR3MCHR1SIGMAR1HRH3 | |
| SCHEMBL5487639 | 0.78 | HRH3 (0.66) | DRD4CXCR3SIGMAR1HRH3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720550-B1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2009-04-15 | — | — | EP | claimed |
| EP-1720550-B1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2009-04-15 | — | — | EP | disclosed |