Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 3/20 | 0.55 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3937208 | 0.88 | MCHR1 (0.62) | DRD4BCHECXCR4SIGMAR1MCHR1 | |
| SCHEMBL23123778 | 0.86 | CCR3 (0.61) | BCHELTA4HSIGMAR1FAAHACHE | |
| SCHEMBL3937679 | 0.83 | DRD4 (0.69) | HRH3DRD4CXCR3SLC6A4SIGMAR1 | |
| SCHEMBL3594120 | 0.81 | MAPT (0.55) | SLC6A4HTR1ACXCR4SIGMAR1 | |
| SCHEMBL3938247 | 0.79 | HTR1A (0.53) | DRD4SLC6A4HTR1ASIGMAR1 | |
| SCHEMBL3594346 | 0.78 | LTA4H (0.55) | BCHELTA4HFAAHACHE | |
| SCHEMBL3598405 | 0.77 | L3MBTL1 (0.50) | HRH3DRD4MAOBLTA4HSIGMAR1 | |
| SCHEMBL3946379 | 0.76 | MCHR1 (0.63) | SIGMAR1MCHR1ACHE | |
| SCHEMBL3938953 | 0.76 | CCR4 (0.58) | HRH3DRD4CXCR3SLC6A4MAOB | |
| SCHEMBL5487639 | 0.76 | HRH3 (0.66) | HRH3DRD4CXCR3SLC6A4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720550-B1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2009-04-15 | — | — | EP | disclosed |