Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3929837 | 0.78 | MAPK1 (0.40) | HPGDNPSR1LMNAKMT2ARXRA | |
| SCHEMBL12450048 | 0.69 | TRPV1 (0.40) | HPGDNPSR1LMNAKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL7049243 | 0.68 | NOS2 (0.61) | — | |
| SCHEMBL3925099 | 0.67 | SYK (0.45) | HTTMAPK1SMN1; SMN2PPARAPPARG | |
| SCHEMBL3928210 | 0.66 | AGBL2 (0.68) | HPGDNPSR1KMT2ARXRARXRB | |
| SCHEMBL3927733 | 0.66 | HSD17B10 (0.42) | KMT2ARXRARXRBALDH1A1HTT | |
| SCHEMBL27641259 | 0.65 | MAPK1 (0.55) | KMT2AMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3924308 | 0.65 | TKT (0.37) | NPSR1KMT2ARXRAALDH1A1MAPK1 | |
| SCHEMBL7205380 | 0.65 | SMN1; SMN2 (0.47) | LMNAKMT2ARXRARXRBALDH1A1 | |
| SCHEMBL13851664 | 0.65 | MAPT (0.51) | NPSR1LMNAALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |