Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.39 |
| ▸ | DDR1 | Q08345 | 5/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3939039 | 0.88 | KDM4E (0.41) | KDM4EALDH1A1MEN1KMT2APKM | |
| SCHEMBL3939019 | 0.84 | GLS (0.43) | CHRM2DDR1KDM4EALDH1A1CHRM3 | |
| SCHEMBL3929761 | 0.77 | NPSR1 (0.47) | CYP1A2CHRM2SLC6A4OPRD1OPRK1 | |
| SCHEMBL3933437 | 0.77 | CCR5 (0.55) | — | |
| Piperazine SCHEMBL27767250 | 0.76 | NPSR1 (0.46) | CYP1A2CHRM2SLC6A4OPRD1OPRK1 | |
| SCHEMBL5738807 | 0.76 | CA5A (0.51) | CYP1A2KDM4EALDH1A1KMT2A | |
| SCHEMBL2126108 | 0.76 | CYP4F2 (0.43) | ALDH1A1PKM | |
| SCHEMBL30154424 | 0.76 | CYP4F2 (0.43) | ALDH1A1PKM | |
| SCHEMBL2127345 | 0.76 | CYP4F2 (0.43) | ALDH1A1PKML3MBTL1 | |
| SCHEMBL4842048 | 0.76 | CA5A (0.58) | CYP1A2KDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044044-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2009-04-08 | — | — | EP | disclosed |
| WO-2007143745-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2007-12-13 | — | — | WO | disclosed |