Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.61 |
| ▸ | MAOB | P27338 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL27942269 | 0.89 | MAOA (0.73) | MAOAMAOBTSHRLMNAMAPT | |
| SCHEMBL72752 | 0.89 | — | — | |
| Fluoride SCHEMBL27481173 | 0.87 | MAOA (0.70) | MAOAMAOBTSHRLMNAMAPT | |
| SCHEMBL4446050 | 0.82 | MAOA (0.64) | MAOAMAOBTSHRLMNAMAPT | |
| SCHEMBL28312718 | 0.80 | MAOA (0.61) | MAOAMAOBTSHRLMNAMAPT | |
| Ammonia Solution, Strong SCHEMBL3940933 | 0.78 | KDM4E (0.53) | MAOAMAOBTSHRCYP2A6CA2 | |
| Ammonia Solution, Strong SCHEMBL27405382 | 0.78 | CA2 (0.65) | MAOAMAOBTSHRCYP2A6CA2 | |
| Benzonitrile SCHEMBL3947588 | 0.77 | TSHR (0.74) | MAOAMAOBTSHRLMNAMAPT | |
| SCHEMBL11390100 | 0.76 | MAOB (0.57) | MAOAMAOBTSHRLMNAMAPT | |
| SCHEMBL11390106 | 0.76 | MAOB (0.57) | MAOAMAOBTSHRLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569606-B2 | Platinum complexes with mononitrile-containing ligands | BIONUMERIK PHARMACEUTICALS, INC. (US) | 2009-08-04 | — | — | US | disclosed |
| US-20070173485-A1 | Amminecyclohexanecarbonitriledichloroplatinum; platinum is capable of rapidly undergoing chelation with the Guanine or Adenine base of a DNA oligonucleotide at the 7 position; readily taken up by tumor cells | JUNIPER NETWORKS, INC. | 2007-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173485-A1 | Amminecyclohexanecarbonitriledichloroplatinum; platinum is capable of rapidly undergoing chelation with the Guanine or Adenine base of a DNA oligonucleotide at the 7 position; readily taken up by tumor cells | RNMT, NSUN2, NUDT1 | MAOA 4422/4885MAOB 4265/4885TSHR 3346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.