Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3939707 | 0.94 | RXFP1 (0.44) | MEN1KMT2A | |
| SCHEMBL3952068 | 0.90 | MEN1 (0.48) | MEN1KMT2ALMNA | |
| SCHEMBL3947537 | 0.90 | MEN1 (0.50) | MEN1KMT2ACTDSP1 | |
| SCHEMBL3951498 | 0.89 | RXFP1 (0.42) | MEN1KMT2ALMNA | |
| SCHEMBL3950864 | 0.89 | LMNA (0.50) | MEN1KMT2ALMNA | |
| SCHEMBL3941781 | 0.89 | TP53 (0.47) | — | |
| SCHEMBL3945382 | 0.89 | TP53 (0.46) | MMP1MMP2MMP9MMP12 | |
| SCHEMBL13942057 | 0.89 | MMP1 (0.41) | MEN1KMT2ALMNAMMP1MMP2 | |
| SCHEMBL3949402 | 0.89 | PKM (0.48) | MEN1KMT2ALMNAMMP1MMP2 | |
| SCHEMBL3947411 | 0.88 | MEN1 (0.50) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |