SCHEMBL394187

SCHEMBL394187

O=C(O)c1cccc(F)c1Br

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALB P02768 1/20 0.61
CES2 O00748 3/20 0.48
CES1 P23141 3/20 0.48
BCHE P06276 1/20 0.48
ALDH1A1 P00352 4/20 0.48
ALOX15 P16050 2/20 0.48
NR4A1 P22736 1/20 0.47
NR4A2 P43354 1/20 0.47
NR4A3 Q92570 1/20 0.47
NAPRT Q6XQN6 2/20 0.44
TAS2R14 Q9NYV8 1/20 0.42
TTR P02766 1/20 0.42
TSHR P16473 1/20 0.42
PRNP P04156 1/20 0.42
KDM4E B2RXH2 2/20 0.41
HPGD P15428 2/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
HMGB1 P09429 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1116170 0.84 ALDH1A1 (0.60) ALBALDH1A1ALOX15NR4A1NR4A2
SCHEMBL9421736 0.83 CES2 (0.48) ALBCES2CES1BCHEALDH1A1
SCHEMBL11135093 0.83 ALB (0.50) ALBCES2CES1BCHEALDH1A1
SCHEMBL27903517 0.81 DGAT1 (0.50) ALBCES2CES1BCHEALDH1A1
SCHEMBL2475914 0.81 KMT2A (0.49) ALBCES2CES1BCHEALDH1A1
SCHEMBL29411082 0.81 KMT2A (0.49) ALBCES2CES1BCHEALDH1A1
SCHEMBL17938254 0.81 ALDH1A1 (0.63) ALBCES2CES1BCHEALDH1A1
SCHEMBL31094955 0.80 CYP1A2 (0.44) ALBCES2CES1ALDH1A1ALOX15
SCHEMBL31298304 0.78 PTPN1 (0.50) ALBCES2CES1BCHEALDH1A1
SCHEMBL27201537 0.78 CES2 (0.47) ALBCES2CES1BCHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 422 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116854631-B 4-Aryl-2-pyridone compound and preparation method thereof 安徽中医药大学 2025-04-15 CN claimed
CN-116854631-A 4-aryl-2-pyridone compound and preparation method thereof 安徽中医药大学 2023-10-10 CN claimed
CN-108003016-B Synthetic method of 2-bromo-3-fluorobenzoic acid 杭州逸翔化工科技有限公司 2020-07-31 CN claimed
CN-108003016-A A kind of synthetic method of the bromo- 3- fluobenzoic acids of 2- 上海晋鲁医药科技有限公司 2018-05-08 CN claimed
WO-2018057219-A1 METHOD OF ALLOCATING INDIVIDUAL OIL OR WATER PRODUCTION CONTRIBUTIONS FROM MULTIPLE COMBINED SOURCES SPECTRUM TRACER SERVICES, LLC (US) 2018-03-29 WO claimed
US-20180080314-A1 METHOD OF ALLOCATING INDIVIDUAL OIL OR WATER PRODUCTION CONTRIBUTIONS FROM MULTIPLE COMBINED SOURCES SPECTRUM TRACER SERVICES, LLC 2018-03-22 US claimed
CN-102898301-A Preparation method of 2-bromine-3-fluorobenzoic acid CHEN WEIDONG 2013-01-30 CN claimed
US-20260132112-A1 COMPOUNDS CTXT PTY LTD (AU) 2026-05-14 US disclosed
US-20260078135-A1 POLYCYCLIC QUINAZOLINES FOR INHIBITION OF ERBB2 ENLIVEN INC (US) 2026-03-19 US disclosed
US-20250382312-A1 BORON CONTAINING PYRAZOLE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF BORAH INC (US) 2025-12-18 US disclosed
US-12486253-B2 Therapeutics for the degradation of mutant BRAF C4 THERAPEUTICS, INC. (US) 2025-12-02 US disclosed
EP-4077318-B1 BENZIMIDAZOLE DIMERS AS MODULATORS OF STING CTXT PTY LTD (AU) 2025-10-15 EP disclosed
US-12415785-B2 Compound modulators of sting CTXT PTY LTD (AU) 2025-09-16 US disclosed
WO-2005067537-A2 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS GLAXO GROUP LIMITED (GB) 2005-07-28 WO disclosed
WO-2004052312-A2 ANTI-INFECTIVES SMITHKLINE BEECHAM CORPORATION (US) 2004-06-24 WO disclosed
US-6369270-B1 CHEMICAL INTERMEDIATES RHONE POULENC AGRICULTURE LIMITED (GB) 2002-04-09 US disclosed
US-20020037888-A1 4-imidazol-1-ylmethyl-2-(2-(2-oxo-piperidin-1-yl)-phenoxy) -benzonitrile for example; farnesyl-protein transferase inhibitors; treating cancer, benign proliferative disorder, hepatitis virus, restenosis, and polycystic kidney disease MERCK & CO., INC. 2002-03-28 US disclosed
US-6284755-B1 Inhibitors of prenyl-protein transferase MERCK & CO., INC. 2001-09-04 US disclosed
WO-2000059930-A1 A METHOD OF TREATING CANCER MERCK & CO., INC. (US) 2000-10-12 WO disclosed
US-4386035-A INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1983-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250382312-A1 BORON CONTAINING PYRAZOLE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF JAK3, JAK1, JAK2 ALB 1858/4885CES2 4765/4885CES1 3747/4885
US-12486253-B2 Therapeutics for the degradation of mutant BRAF BRAF, NRAS, KRAS ALB 1493/4885CES2 4488/4885CES1 3827/4885
US-12415785-B2 Compound modulators of sting STING1, IRF3, MAVS ALB 4869/4885CES2 4411/4885CES1 3481/4885
US-20260132112-A1 COMPOUNDS STING1, IRF3, CGAS ALB 4729/4885CES2 1583/4885CES1 967/4885
US-20260078135-A1 POLYCYCLIC QUINAZOLINES FOR INHIBITION OF ERBB2 ERBB2, BRCA1, ERBB3 ALB 4826/4885CES2 2700/4885CES1 383/4885
US-20020037888-A1 4-imidazol-1-ylmethyl-2-(2-(2-oxo-piperidin-1-yl)-phenoxy) -benzonitrile for example; farnesyl-protein transferase inhibitors; treating cancer, benign proliferative disorder, hepatitis virus, restenosis, and polycystic kidney disease FNTA, PKD1, FNTB ALB 1612/4885CES2 3261/4885CES1 361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.