Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5451 | 0.91 | SMN1; SMN2 (0.51) | NPC1RAB9ASMN1; SMN2MAPK1AR | |
| SCHEMBL30283197 | 0.91 | SMN1; SMN2 (0.51) | NPC1RAB9ASMN1; SMN2MAPK1AR | |
| Hydrochloric Acid SCHEMBL27764098 | 0.89 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2MAPK1AR | |
| Ammonia Solution, Strong SCHEMBL3942484 | 0.80 | POLB (0.56) | NPC1RAB9ASMN1; SMN2ARALDH1A1 | |
| SCHEMBL1132618 | 0.77 | PIP4K2A (0.48) | ARALDH1A1GAAPOLBNPSR1 | |
| SCHEMBL20607680 | 0.77 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2MAPK1AR | |
| SCHEMBL973234 | 0.77 | ALDH1A1 (0.54) | NPC1RAB9ASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL10499090 | 0.76 | ALDH1A1 (0.53) | NPC1RAB9ASMN1; SMN2MAPK1ALDH1A1 | |
| Acetoacetic Acid SCHEMBL27513054 | 0.75 | SMN1; SMN2 (0.52) | NPC1RAB9ASMN1; SMN2MAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL13857771 | 0.75 | ALDH1A1 (0.53) | NPC1RAB9ASMN1; SMN2MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569606-B2 | Platinum complexes with mononitrile-containing ligands | BIONUMERIK PHARMACEUTICALS, INC. (US) | 2009-08-04 | — | — | US | disclosed |
| US-20070173485-A1 | Amminecyclohexanecarbonitriledichloroplatinum; platinum is capable of rapidly undergoing chelation with the Guanine or Adenine base of a DNA oligonucleotide at the 7 position; readily taken up by tumor cells | JUNIPER NETWORKS, INC. | 2007-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173485-A1 | Amminecyclohexanecarbonitriledichloroplatinum; platinum is capable of rapidly undergoing chelation with the Guanine or Adenine base of a DNA oligonucleotide at the 7 position; readily taken up by tumor cells | RNMT, NSUN2, NUDT1 | NPC1 3447/4885RAB9A 2814/4885SMN1; SMN2 1417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.