Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 3/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982321 | 0.79 | CYP1A2 (0.55) | CYP1A2CYP2C19CYP2C9CYP3A4ALDH1A1 | |
| SCHEMBL10347703 | 0.77 | CYP1A2 (0.38) | CYP1A2CYP2C19CYP2C9KCNH2CYP3A4 | |
| SCHEMBL9742504 | 0.77 | CYP1A2 (0.55) | CYP1A2CYP2C19CYP2C9CYP3A4ALDH1A1 | |
| SCHEMBL12961840 | 0.76 | KCNH2 (0.42) | CYP1A2CYP2C19CYP2C9KCNH2ALDH1A1 | |
| SCHEMBL6161775 | 0.76 | KCNH2 (0.42) | CYP1A2CYP2C19CYP2C9KCNH2ALDH1A1 | |
| SCHEMBL13951737 | 0.76 | KCNH2 (0.42) | CYP1A2CYP2C19CYP2C9KCNH2ALDH1A1 | |
| SCHEMBL14765557 | 0.76 | KCNH2 (0.42) | CYP1A2CYP2C19CYP2C9KCNH2ALDH1A1 | |
| SCHEMBL6163980 | 0.76 | KCNH2 (0.47) | CYP1A2CYP2C9KCNH2CYP3A4ALDH1A1 | |
| SCHEMBL2882586 | 0.75 | ALDH1A1 (0.38) | CYP1A2CYP2C19CYP2C9KCNH2CYP3A4 | |
| SCHEMBL2882585 | 0.75 | ALDH1A1 (0.38) | CYP1A2CYP2C19CYP2C9KCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394974-B2 | Process for producing optically active chromene oxide compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-03-12 | — | — | US | disclosed |
| EP-2003135-A9 | PROCESS FOR PRODUCING OPTICALLY ACTIVE CHROMENE OXIDE COMPOUND | Nissan Chemical Industries, Ltd. (JP) | 2009-04-22 | — | — | EP | disclosed |
| US-20090043100-A1 | Process for Producing Optically Active Chromene Oxide Compound | NISSAN CHEMICAL INDUSTRIES, LTD (JP) | 2009-02-12 | — | — | US | disclosed |
| EP-2003135-A2 | PROCESS FOR PRODUCING OPTICALLY ACTIVE CHROMENE OXIDE COMPOUND | Nissan Chemical Industries, Ltd. (JP) | 2008-12-17 | — | — | EP | disclosed |
| US-6809114-B2 | ANTIARRHYTHMIC AGENTS; SUCH AS 6-ACETYLAMINO-3,4-DIHYDRO-2,2-DIMETHYL-7-NITRO-4-N-PENTYLAMINO-2H-1 -BENZOPYRAN-3-OL | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2004-10-26 | — | — | US | disclosed |
| EP-1360182-B1 | 4-AMINOBENZOPYRAN DERIVATIVES | NISSAN CHEMICAL IND LTD (JP) | 2004-08-11 | — | — | EP | disclosed |
| US-20040068002-A1 | 4-aminobenzopyran derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2004-04-08 | — | — | US | disclosed |
| EP-1360182-A1 | 4-AMINOBENZOPYRAN DERIVATIVES | Nissan Chemical Industries, Ltd. (JP) | 2003-11-12 | — | — | EP | disclosed |
| WO-2002064581-A1 | 4-AMINOBENZOPYRAN DERIVATIVES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2002-08-22 | — | — | WO | disclosed |
| EP-0571822-B1 | Diazabicycloalkene derivatives | DAIICHI SEIYAKU CO (JP) | 2001-08-16 | — | — | EP | disclosed |
| CN-1061346-C | Diazabicycloalkene derivatives | DAIICHI SEIYAKU CO (JP) | 2001-01-31 | — | — | CN | disclosed |
| US-5418232-A | Hypotensive, increases renal blood flow | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-05-23 | — | — | US | disclosed |
| CN-1082042-A | Diazabicycloalkene derivatives | DAIICHI SEIYAKU CO (JP) | 1994-02-16 | — | — | CN | disclosed |
| EP-0571822-A1 | Diazabicycloalkene derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040068002-A1 | 4-aminobenzopyran derivatives | CYP2D6, KCNH1, CYP2B6 | CYP1A2 47/4885CYP2C19 210/4885CYP2C9 49/4885 |
| US-20090043100-A1 | Process for Producing Optically Active Chromene Oxide Compound | CYP2C19, CYP2C9, CYP1A2 | CYP1A2 3/4885CYP2C19 1/4885CYP2C9 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.