Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3950669 | 0.90 | MEN1 (0.56) | GAATSHRBLM | |
| SCHEMBL3950693 | 0.89 | MMP1 (0.42) | TSHRCA1CA2 | |
| SCHEMBL3950845 | 0.84 | MEN1 (0.58) | — | |
| SCHEMBL13942736 | 0.84 | MEN1 (0.57) | — | |
| SCHEMBL3944323 | 0.83 | MEN1 (0.56) | GAATSHRBLM | |
| SCHEMBL3948655 | 0.82 | RXFP1 (0.61) | TSHR | |
| SCHEMBL3944977 | 0.82 | RXFP1 (0.44) | TSHRCA1CA2 | |
| SCHEMBL3944709 | 0.81 | PKM (0.57) | GAATSHRBLM | |
| SCHEMBL13942600 | 0.81 | MEN1 (0.54) | GAATSHRBLM | |
| SCHEMBL3950017 | 0.81 | ALDH1A1 (0.62) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |