Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3941421 | 0.81 | AKR1C3 (0.36) | AKR1C3LIPETSHRL3MBTL1POLB | |
| SCHEMBL3951275 | 0.72 | PDE4A (0.37) | LIPETSHRPOLBSMN1; SMN2TDP1 | |
| SCHEMBL3943563 | 0.72 | POLB (0.36) | LIPETSHRPOLBSMN1; SMN2TDP1 | |
| SCHEMBL3944735 | 0.71 | HTR2A (0.39) | LIPETSHRPOLBSMN1; SMN2TDP1 | |
| SCHEMBL3942636 | 0.70 | ALDH1A1 (0.38) | TSHRL3MBTL1POLBSMN1; SMN2TDP1 | |
| SCHEMBL6576703 | 0.65 | L3MBTL1 (0.47) | AKR1C3TSHRL3MBTL1MEN1KMT2A | |
| SCHEMBL3946661 | 0.64 | KMT2A (0.33) | TSHRPOLBSMN1; SMN2TDP1TRPV1 | |
| SCHEMBL10642825 | 0.64 | L3MBTL1 (0.41) | AKR1C3TSHRL3MBTL1P2RX3MAPT | |
| SCHEMBL4192247 | 0.61 | TRPV1 (0.34) | TSHRL3MBTL1POLBSMN1; SMN2TDP1 | |
| SCHEMBL30919778 | 0.61 | MAPK8 (0.42) | AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019099-A1 | TETRASUBSTITUTED PYRIMIDINE DERIVATIVES FOR CONTROLLING PHYTOPATHOGENIC FUNGI | BASF SE (DE) | 2009-02-12 | — | — | WO | disclosed |