Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | PYGL | P06737 | 6/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3945345 | 0.90 | ALDH1A1 (0.42) | ALDH1A1KMT2AMAPTL3MBTL1MAPK14 | |
| SCHEMBL3943464 | 0.90 | ALDH1A1 (0.44) | ALDH1A1KMT2AMAPTL3MBTL1MAPK14 | |
| SCHEMBL3950664 | 0.88 | MAPT (0.52) | ALDH1A1KMT2AMAPTL3MBTL1RAB9A | |
| SCHEMBL4362231 | 0.88 | MAPT (0.52) | ALDH1A1KMT2AMAPTL3MBTL1RAB9A | |
| SCHEMBL3944227 | 0.88 | DGAT1 (0.40) | ALDH1A1KMT2AMAPTL3MBTL1PYGL | |
| SCHEMBL4212851 | 0.88 | RAB9A (0.49) | ALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL3945898 | 0.83 | ALDH1A1 (0.51) | ALDH1A1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL3949749 | 0.82 | RAB9A (0.41) | ALDH1A1KMT2AMAPTL3MBTL1RAB9A | |
| SCHEMBL4032664 | 0.82 | RAB9A (0.42) | ALDH1A1MAPTL3MBTL1RAB9ANPC1 | |
| SCHEMBL4357051 | 0.81 | RAB9A (0.43) | ALDH1A1KMT2AMAPTL3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | claimed |
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |