SCHEMBL394436

SCHEMBL394436

C=CC(=O)OCCC[SiH2]C(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.50
ALDH1A1 P00352 4/20 0.50
CYP3A4 P08684 2/20 0.50
HPGD P15428 1/20 0.50
TP53 P04637 3/20 0.42
HIF1A Q16665 3/20 0.42
HSD17B10 Q99714 1/20 0.42
THRB P10828 2/20 0.36
ATM Q13315 1/20 0.33
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30784998 0.91 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL4883024 0.91 TSHR (0.42) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL397194 0.90 TSHR (0.44) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL29939024 0.90 TSHR (0.51) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL3478325 0.90 TSHR (0.46) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL23493061 0.86 TSHR (0.38) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL15255023 0.85 TSHR (0.49) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL140890 0.84 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL35613 0.83 ATM (0.40) TSHRALDH1A1CYP3A4HPGDATM
SCHEMBL397012 0.82 TSHR (0.43) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7282550-B2 Composition to provide a layer with uniform etch characteristics MOLECULAR IMPRINTS, INC. (US) 2007-10-16 US claimed
US-20060035029-A1 Method to provide a layer with uniform etch characteristics MOLECULAR IMPRINTS, INC. (US) 2006-02-16 US claimed
US-20060036051-A1 Composition to provide a layer with uniform etch characteristics MOLECULAR IMPRINTS, INC. (US) 2006-02-16 US claimed
US-20260015525-A1 ARTICLE FIXTURE, METHOD FOR REMOVING ARTICLE, AND ADHESIVE SHEET UNIT SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-01-15 US disclosed
EP-4561513-A1 ARTICLE FIXTURE, METHOD FOR REMOVING ARTICLE, AND ADHESIVE SHEET UNIT Solventum Intellectual Properties Company (US) 2025-06-04 EP disclosed
CN-119630371-A Article fixing device, method for removing article, and adhesive sheet unit 舒万诺知识产权公司 2025-03-14 CN disclosed
US-12097497-B2 Cell accommodating chip YAMATO SCIENTIFIC CO., LTD. (JP) 2024-09-24 US disclosed
WO-2024023617-A1 ARTICLE FIXTURE, METHOD FOR REMOVING ARTICLE, AND ADHESIVE SHEET UNIT 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-02-01 WO disclosed
CN-113429579-B Strong-adsorption branched tertiary amine silanol serving as shale surface hydration inhibitor 西南石油大学 2022-09-30 CN disclosed
US-20120231234-A1 CURABLE COMPOSITION FOR IMPRINTS, PATTERNING METHOD AND PATTERN FUJIFILM CORPORATION (JP) 2012-09-13 US disclosed
US-8110697-B2 Method for the production of polymerizable silicones WACKER CHEMIE AG (DE) 2012-02-07 US disclosed
US-8101789-B2 Method for the production of polymerizable silicones WACKER CHEMIE AG (DE) 2012-01-24 US disclosed
EP-2125833-B1 METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES WACKER CHEMIE AG (DE) 2010-08-25 EP disclosed
EP-2125834-B1 METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES WACKER CHEMIE AG (DE) 2010-08-25 EP disclosed
US-20100041909-A1 METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES WACKER CHEMIE AG (DE) 2010-02-18 US disclosed
US-20100029972-A1 METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES WACKER CHEMIE AG (DE) 2010-02-04 US disclosed
US-7282550-B2 Composition to provide a layer with uniform etch characteristics MOLECULAR IMPRINTS, INC. (US) 2007-10-16 US disclosed
US-4743667-A ACRYLATED SILOXXANES, OXYGEN PERMEABLE NIPPON CONTACT LENS, INC. (JP) 1988-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015525-A1 ARTICLE FIXTURE, METHOD FOR REMOVING ARTICLE, AND ADHESIVE SHEET UNIT STUB1, TLN1, ICAM1 TSHR 1544/4885ALDH1A1 1950/4885CYP3A4 4738/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.