Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPI | P34949 | 12/20 | 0.57 |
| ▸ | PMM2 | O15305 | 10/20 | 0.57 |
| ▸ | PHOSPHO1 | Q8TCT1 | 9/20 | 0.57 |
| ▸ | G6PD | P11413 | 8/20 | 0.57 |
| ▸ | APOBEC3G | Q9HC16 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.57 |
| ▸ | CASP3 | P42574 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | IDE | P14735 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3948605 | 0.83 | G6PD (0.61) | MPIPMM2PHOSPHO1G6PDAPOBEC3G | |
| SCHEMBL8369484 | 0.80 | MPI (0.57) | MPIPMM2PHOSPHO1G6PDAPOBEC3G | |
| SCHEMBL8373396 | 0.80 | MPI (0.57) | MPIPMM2PHOSPHO1G6PDAPOBEC3G | |
| SCHEMBL8371816 | 0.80 | MPI (0.57) | MPIPMM2PHOSPHO1G6PDAPOBEC3G | |
| SCHEMBL8369537 | 0.80 | MPI (0.57) | MPIPMM2PHOSPHO1G6PDAPOBEC3G | |
| SCHEMBL8370777 | 0.78 | PHOSPHO1 (0.55) | MPIPMM2PHOSPHO1G6PDAPOBEC3G | |
| SCHEMBL3955200 | 0.76 | MPI (0.56) | MPIPMM2PHOSPHO1G6PDAPOBEC3G | |
| SCHEMBL30562926 | 0.73 | MPI (1.00) | MPIPMM2PHOSPHO1G6PDAPOBEC3G | |
| SCHEMBL1898397 | 0.73 | MPI (1.00) | MPIPMM2PHOSPHO1G6PDAPOBEC3G | |
| SCHEMBL30738364 | 0.72 | MPI (0.96) | MPIPMM2PHOSPHO1G6PDAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1655290-B1 | Compositions comprising a benzoisothiazolone derivative and their use in the cosmetic field | OREAL (FR) | 2009-04-29 | — | — | EP | claimed |
| US-7232839-B2 | Benzoisothiazolone compositions | L'OREAL (FR) | 2007-06-19 | — | — | US | claimed |
| US-20060142587-A1 | Benzoisothiazolone compositions | L'OREAL (FR) | 2006-06-29 | — | — | US | claimed |
| EP-1655290-A1 | Compositions comprising a benzoisothiazolone derivative and their use in the cosmetic field | L'OREAL (FR) | 2006-05-10 | — | — | EP | claimed |
| WO-2024008788-A1 | USE OF EBSELEN OR ONE OF THE DERIVATIVES THEREOF TO TREAT MITOCHONDRIAL PATHOLOGIES OR DYSFUNCTIONS | ASSOCIATION FRANCAISE CONTRE LES MYOPATHIES (FR) | 2024-01-11 | — | — | WO | disclosed |
| EP-1655290-B1 | Compositions comprising a benzoisothiazolone derivative and their use in the cosmetic field | OREAL (FR) | 2009-04-29 | — | — | EP | disclosed |
| US-7232839-B2 | Benzoisothiazolone compositions | L'OREAL (FR) | 2007-06-19 | — | — | US | disclosed |
| US-20060142587-A1 | Benzoisothiazolone compositions | L'OREAL (FR) | 2006-06-29 | — | — | US | disclosed |
| EP-1655290-A1 | Compositions comprising a benzoisothiazolone derivative and their use in the cosmetic field | L'OREAL (FR) | 2006-05-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142587-A1 | Benzoisothiazolone compositions | COL1A1, TYR, CUTA | MPI 3471/4885PMM2 4486/4885PHOSPHO1 2553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.