Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15812122 | 0.85 | AAK1 (0.37) | AAK1MTNR1AMTNR1BATRMEN1 | |
| SCHEMBL8288755 | 0.84 | ATR (0.34) | AAK1MTNR1AMTNR1BATRMEN1 | |
| SCHEMBL6028212 | 0.83 | KMT2A (0.41) | MTNR1AMTNR1BMEN1KMT2APABPC1 | |
| SCHEMBL21591747 | 0.81 | MTNR1B (0.46) | AAK1MTNR1AMTNR1BALDH1A1MAPT | |
| SCHEMBL29713519 | 0.80 | NNMT (0.47) | AAK1ATRMEN1KMT2APABPC1 | |
| SCHEMBL7681674 | 0.80 | NNMT (0.47) | AAK1ATRMEN1KMT2APABPC1 | |
| SCHEMBL12513167 | 0.79 | ATR (0.38) | AAK1ATRMEN1KMT2APABPC1 | |
| SCHEMBL20095986 | 0.79 | MEN1 (0.38) | AAK1MTNR1AMTNR1BATRMEN1 | |
| SCHEMBL28391719 | 0.79 | NNMT (0.39) | AAK1ATRMEN1KMT2APABPC1 | |
| SCHEMBL1430094 | 0.79 | ATR (0.38) | AAK1MTNR1AMTNR1BATRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117088874-A | Diacylglycerol kinase inhibitors and uses thereof | 轩竹生物科技股份有限公司 | 2023-11-21 | — | — | CN | disclosed |
| WO-2009034546-A2 | TRANS-DECAHYDROISOQUINOLINE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2009-03-19 | — | — | WO | disclosed |
| WO-2009034546-A2 | TRANS-DECAHYDROISOQUINOLINE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2009-03-19 | — | — | WO | disclosed |
| WO-2005040168-A1 | AZABENZODIAZEPINES AS PHOSPHODIESTERASE-4 INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2005-05-06 | — | — | WO | disclosed |