Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 2/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.32 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | IAPP | P10997 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3946037 | 0.83 | TAAR1 (0.46) | CES2CES1FFAR1DAO | |
| SCHEMBL3940845 | 0.82 | FFAR1 (0.51) | FFAR1FFAR4SLC5A1SLC5A2 | |
| SCHEMBL23662782 | 0.76 | IAPP (0.53) | CES2CES1DAOSLC5A1SLC5A2 | |
| SCHEMBL13574164 | 0.75 | F2RL1 (0.46) | DAO | |
| SCHEMBL925108 | 0.74 | KEAP1 (0.55) | FFAR1FFAR4MCL1 | |
| SCHEMBL3945867 | 0.73 | FFAR1 (0.42) | CES2CES1FFAR1FFAR4DAO | |
| SCHEMBL1448093 | 0.72 | KEAP1 (0.52) | FFAR1FFAR4ACLY | |
| SCHEMBL3937604 | 0.71 | FFAR1 (0.46) | FFAR1 | |
| SCHEMBL17967141 | 0.71 | PLAAT3 (0.45) | FFAR1 | |
| SCHEMBL5644564 | 0.71 | FFAR1 (0.48) | CES2CES1FFAR1FFAR4DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016410-A2 | CHEMICAL COMPOUNDS 831 | ASTRAZENECA AB (SE) | 2009-02-05 | — | — | WO | disclosed |