Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3947865 | 0.83 | F2 (0.36) | HSD17B10ALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL3939417 | 0.69 | SSTR4 (0.41) | AGBL2HDAC1HDAC6 | |
| SCHEMBL16055505 | 0.67 | KMT2A (0.35) | HSD17B10ALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL19086382 | 0.67 | PTK2 (0.43) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL28453095 | 0.65 | AGBL2 (0.39) | AGBL2HCAR2L3MBTL1 | |
| SCHEMBL3822535 | 0.65 | OXTR (0.43) | HSD17B10ALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL1920711 | 0.65 | GBA1 (0.44) | HSD17B10ALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL10941853 | 0.64 | MEN1 (0.49) | HSD17B10ALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL1396052 | 0.64 | AGBL2 (0.38) | ALDH1A1AGBL2RAB9AMAPTKMT2A | |
| SCHEMBL25552302 | 0.64 | AGBL2 (0.33) | AGBL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016410-A2 | CHEMICAL COMPOUNDS 831 | ASTRAZENECA AB (SE) | 2009-02-05 | — | — | WO | disclosed |