Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28061498 | 0.80 | HTT (0.34) | AGBL2PIK3C3HTTSSTR4 | |
| SCHEMBL7969124 | 0.73 | ALDH1A1 (0.44) | AGBL2HTTL3MBTL1 | |
| SCHEMBL21801501 | 0.72 | NAPRT (0.41) | HTTL3MBTL1 | |
| SCHEMBL1395991 | 0.68 | AGBL2 (0.41) | AGBL2L3MBTL1HCAR2 | |
| SCHEMBL25552302 | 0.68 | AGBL2 (0.33) | AGBL2HTT | |
| SCHEMBL3944952 | 0.65 | HSD17B10 (0.37) | AGBL2L3MBTL1HCAR2 | |
| SCHEMBL4326940 | 0.64 | DPP4 (0.39) | AGBL2HCAR2 | |
| SCHEMBL30641925 | 0.64 | DPP4 (0.39) | AGBL2HCAR2 | |
| Acetic Acid SCHEMBL15094229 | 0.64 | AGBL2 (0.38) | AGBL2HCAR2 | |
| SCHEMBL22788157 | 0.64 | PDK2 (0.38) | AGBL2SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111635408-B | Triazolo-pyrimidine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-112279852-A | Triazolo-pyrimidine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2021-01-29 | — | — | CN | disclosed |
| CN-111601809-A | Triazolo-pyrimidine compounds and uses thereof | 迪哲（江苏）医药有限公司 | 2020-08-28 | — | — | CN | disclosed |