Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3947871 | 0.84 | S1PR3 (0.39) | S1PR3IRAK4 | |
| SCHEMBL31448001 | 0.78 | AGBL2 (0.32) | AGBL2 | |
| SCHEMBL3938021 | 0.78 | AGBL2 (0.32) | AGBL2 | |
| SCHEMBL4023229 | 0.77 | APLNR (0.41) | AGBL2GRM5MAPK1ABL1 | |
| SCHEMBL1395922 | 0.75 | TAAR1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL4974376 | 0.74 | TAAR1 (0.32) | — | |
| SCHEMBL4019098 | 0.73 | MAPK1 (0.39) | AGBL2GRM5PTGER4MAPK1 | |
| SCHEMBL21862847 | 0.72 | MAPK1 (0.51) | AGBL2S1PR1S1PR3GRM5PTGER4 | |
| SCHEMBL28448235 | 0.72 | MAPK1 (0.41) | AGBL2S1PR1S1PR3ADORA2AGRM5 | |
| SCHEMBL12985296 | 0.70 | MEN1 (0.44) | AGBL2S1PR1S1PR3CYP2C19MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016410-A2 | CHEMICAL COMPOUNDS 831 | ASTRAZENECA AB (SE) | 2009-02-05 | — | — | WO | disclosed |