Benzene

Benzene

SCHEMBL394543

CCCC.c1ccccc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.38
TP53 P04637 2/20 0.38
LMNA P02545 2/20 0.36
CHRM2 P08172 2/20 0.33
ADRA2A P08913 2/20 0.33
ADORA3 P0DMS8 2/20 0.33
CHRM1 P11229 2/20 0.33
ACHE P22303 2/20 0.33
SLC6A2 P23975 2/20 0.33
SLC6A4 P31645 2/20 0.33
SLC6A3 Q01959 2/20 0.33
THRB P10828 1/20 0.33
ABCB11 O95342 1/20 0.33
ESR1 P03372 1/20 0.33
PGR P06401 1/20 0.33
HTR1A P08908 1/20 0.33
DRD1 P21728 1/20 0.33
TBXA2R P21731 1/20 0.33
PTGS1 P23219 1/20 0.33
PDE4A P27815 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL11876727 0.94 TP53 (0.35) TSHRTP53LMNACHRM2ADRA2A
Benzene SCHEMBL28335456 0.94 TP53 (0.35) TSHRTP53LMNACHRM2ADRA2A
Benzene SCHEMBL28179681 0.94 TP53 (0.35) TSHRTP53LMNACHRM2ADRA2A
Benzene SCHEMBL27715348 0.94 TP53 (0.35) TSHRTP53LMNACHRM2ADRA2A
Benzene SCHEMBL27521535 0.89 TP53 (0.33) TSHRTP53LMNACHRM2ADRA2A
Butane SCHEMBL7258069 0.80
Butane SCHEMBL2140500 0.80 TSHR (0.44) TSHRLMNACHRM1SLC6A3THRB
Butane SCHEMBL4594497 0.80 TSHR (0.44) TSHRLMNACHRM1SLC6A3THRB
Benzene SCHEMBL286496 0.80
Butane SCHEMBL8628663 0.79 TSHR (0.50) TSHRTP53LMNATHRBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1806 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12612880-B2 Engine lubricant optimization for advanced sustainable fuels ExxonMobil Technology and Engineering Company (US) 2026-04-28 US claimed
US-20260018256-A1 AN ODOR PREDICTION METHOD FOR AQUEOUS POLYMER COMPOSITION DOW GLOBAL TECHNOLOGIES LLC (US) 2026-01-15 US claimed
US-20250250460-A1 COATING KIT AND METHOD FOR REPAIR AND/OR RECONSTITUTION OF RUBBER AND/OR METAL WORN AREAS BERTECH PANAMA S.A. (PA) 2025-08-07 US claimed
US-20250215838-A1 ENGINE LUBRICANT OPTIMIZATION FOR ADVANCED SUSTAINABLE FUELS ExxonMobil Technology and Engineering Company (US) 2025-07-03 US claimed
US-20250174664-A1 COMPOSITION FOR FORMING A POSITIVE ACTIVE MATERIAL LAYER FOR AN ALL-SOLID SECONDARY BATTERY, AND METHOD OF PREPARING A POSITIVE ELECTRODE LAYER FOR AN ALL-SOLID SECONDARY BATTERY SAMSUNG SDI CO LTD (KR) 2025-05-29 US claimed
EP-4551937-A1 AN ODOR PREDICTION METHOD FOR AQUEOUS POLYMER COMPOSITION Dow Global Technologies LLC (US) 2025-05-14 EP claimed
CN-115007201-B Micropore/mesoporous composite SAPO-5 molecular sieve solid acid catalyst, and preparation method and application thereof 浙江工业大学 2024-12-10 CN claimed
CN-115010569-B Method for synthesizing straight-chain alkyl aromatic hydrocarbon 浙江工业大学 2024-07-19 CN claimed
US-12037931-B2 Device increasing engine efficiency and reducing exhaust and noise MA, SZU CHENG (TW) 2024-07-16 US claimed
CN-113620770-B Divinylbenzene separation system and separation method 中国石油化工股份有限公司 2024-05-03 CN claimed
EP-0189683-A1 Alkylation of organic aromatic compounds CHEMICAL RESEARCH & LICENSING COMPANY (US) 1986-08-06 EP claimed
EP-0105063-A1 Liquid hard-surface cleaner THE PROCTER & GAMBLE COMPANY (US) 1984-04-11 EP claimed
US-4350668-A DISTILLATION, SOLVENT EXTRACTION OF RESIDUE, NEUTRALIZATION, PRECIPITATION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1982-09-21 US claimed
US-4246421-A METAL PHOSPHATE CATALYST THE STANDARD OIL COMPANY (US) 1981-01-20 US claimed
US-4098627-A Solvolytic degradation of pyrotechnic materials containing crosslinked polymers THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1978-07-04 US claimed
US-4049740-A WASHING WITH A PARAFFINIC HYDROCARBON SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-09-20 US claimed
US-4003804-A Method of electroplating of aluminum and plating baths therefor SCIENTIFIC MINING & MANUFACTURING COMPANY (US) 1977-01-18 US claimed
US-3997410-A Electrodeposition of aluminum GILEADI ELIEZER 1976-12-14 US claimed
US-3957897-A CATALYZED BY A CALCIUM, MAGNESIUM OR STRONTIUM PYROPHOSPHATE THE DOW CHEMICAL COMPANY (US) 1976-05-18 US claimed
US-3937739-A OXIDATION, DIETHYLBENZENE, DIETHYLBENZENE HYDROPEROXIDE, SUPERBASIC SULFONATES LABOFINA S. A. (BE) 1976-02-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12612880-B2 Engine lubricant optimization for advanced sustainable fuels TST, TCF4, MLLT1 TSHR 3299/4885TP53 576/4885LMNA 4813/4885
US-20260018256-A1 AN ODOR PREDICTION METHOD FOR AQUEOUS POLYMER COMPOSITION OR10J3, OR51E2, TAS2R42 TSHR 4714/4885TP53 1606/4885LMNA 4590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.