Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1408521 | 0.82 | ALDH1A1 (0.53) | ALDH1A1MAPTKMT2AGLAHSD17B10 | |
| Benzene SCHEMBL27977946 | 0.82 | ALDH1A1 (0.53) | ALDH1A1MAPTKMT2AGLAHSD17B10 | |
| SCHEMBL5155844 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MAPTKMT2AGLAHSD17B10 | |
| SCHEMBL28249684 | 0.81 | ALDH1A1 (0.47) | ALDH1A1MAPTKMT2AGLAHSD17B10 | |
| SCHEMBL6086661 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPTKMT2AGLAHSD17B10 | |
| SCHEMBL28360990 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPTKMT2AGLAHSD17B10 | |
| SCHEMBL31058267 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MAPTKMT2AGLAHSD17B10 | |
| Lithium Ion SCHEMBL6086653 | 0.79 | MAPT (0.47) | ALDH1A1MAPTKMT2AGLAHSD17B10 | |
| SCHEMBL2145539 | 0.77 | MAPT (0.45) | ALDH1A1MAPTKMT2AGLAHSD17B10 | |
| SCHEMBL10827381 | 0.77 | MAPT (0.45) | ALDH1A1MAPTKMT2AGLAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6888010-B2 | Process for the preparation of 5-formylphthalide | INFOSINT SA (CH) | 2005-05-03 | — | — | US | claimed |
| US-7482476-B2 | Process for the preparation of 5-cyanophthalide starting from 5-carboxyphthalide | ADORKEM TECHNOLOGY SPA (IT) | 2009-01-27 | — | — | US | disclosed |
| US-20070117991-A1 | Process for the preparation of 5-cyanophthalide starting from 5-carboxyphthalide | ADORKEM TECHNOLOGY SPA (IT) | 2007-05-24 | — | — | US | disclosed |
| EP-1777221-A1 | Process for the preparation of 5-cyanophthalide starting from 5-carboxyphthalide | Adorkem Technology SpA (IT) | 2007-04-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117991-A1 | Process for the preparation of 5-cyanophthalide starting from 5-carboxyphthalide | HTR5A, TPH1, TPH2 | ALDH1A1 625/4885MAPT 2096/4885KMT2A 1994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.