Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3946281 | 0.91 | PTGES (0.41) | ROCK2MMP1MMP2MMP9MMP12 | |
| SCHEMBL3950166 | 0.90 | ROCK2 (0.37) | ROCK2MMP1MMP2MMP9MMP12 | |
| SCHEMBL3951590 | 0.88 | FGFR1 (0.42) | PKMMMP1MMP2MMP9MMP12 | |
| SCHEMBL3943049 | 0.87 | HTT (0.48) | PKMMAPTGAAHTT | |
| SCHEMBL13942745 | 0.86 | PKM (0.51) | PKMMMP1MMP2MMP9MMP12 | |
| SCHEMBL13942747 | 0.84 | PKM (0.51) | PKMMMP1MMP2MMP9MMP12 | |
| SCHEMBL3943430 | 0.81 | PKM (0.58) | PKMRXFP1 | |
| SCHEMBL3946602 | 0.81 | PKM (0.61) | PKMRXFP1 | |
| SCHEMBL3942563 | 0.81 | RXFP1 (0.49) | PKMRXFP1 | |
| SCHEMBL3945411 | 0.81 | RXFP1 (0.58) | PKMRXFP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |