Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.41 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP12 | P39900 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3946162 | 0.91 | PKM (0.41) | DGAT2MMP1MMP12ROCK2MMP2 | |
| SCHEMBL3950166 | 0.88 | ROCK2 (0.37) | MMP1MMP12ROCK2MMP2MMP9 | |
| SCHEMBL3949585 | 0.86 | TSHR (0.51) | PTGESMMP1MMP12TSHRMEN1 | |
| SCHEMBL3945158 | 0.80 | PKM (0.55) | PTGESTSHR | |
| SCHEMBL3945195 | 0.79 | TSHR (0.44) | PTGESMMP1MMP12TSHRMEN1 | |
| SCHEMBL3951590 | 0.79 | FGFR1 (0.42) | MMP1MMP12MMP2MMP9GAA | |
| SCHEMBL3942868 | 0.78 | HTT (0.45) | MEN1KMT2AGAA | |
| SCHEMBL3943049 | 0.78 | HTT (0.48) | TSHRKDM4EMEN1KMT2AGAA | |
| SCHEMBL13942063 | 0.78 | FGFR1 (0.42) | MMP1MMP12MEN1KMT2AMMP2 | |
| SCHEMBL13942067 | 0.77 | HTT (0.46) | TSHRKDM4EMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |