Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | GUSB | P08236 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3945158 | 0.90 | PKM (0.55) | TSHRPTGESTP53GUSB | |
| SCHEMBL13942745 | 0.89 | PKM (0.51) | MEN1KMT2AMMP1MMP12 | |
| SCHEMBL13942600 | 0.89 | MEN1 (0.54) | TSHRMEN1KMT2A | |
| SCHEMBL3942563 | 0.88 | RXFP1 (0.49) | MEN1KMT2A | |
| SCHEMBL13941770 | 0.88 | LMNA (0.47) | MEN1KMT2AMMP1MMP12 | |
| SCHEMBL3945900 | 0.87 | HTT (0.54) | TSHRMEN1KMT2APTGESMMP1 | |
| SCHEMBL3946281 | 0.86 | PTGES (0.41) | TSHRMEN1KMT2APTGESMMP1 | |
| SCHEMBL3945195 | 0.86 | TSHR (0.44) | TSHRMEN1KMT2APTGESMMP1 | |
| SCHEMBL13942736 | 0.84 | MEN1 (0.57) | MEN1KMT2A | |
| SCHEMBL3945411 | 0.82 | RXFP1 (0.58) | TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |