Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.67 |
| ▸ | CNR1 | P21554 | 8/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TYR | P14679 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3948637 | 0.93 | CNR2 (0.60) | CNR2CNR1MEN1KMT2AALOX15 | |
| SCHEMBL3950873 | 0.91 | CNR2 (0.57) | CNR2CNR1MEN1KMT2AALOX15 | |
| SCHEMBL3034727 | 0.90 | CNR2 (0.57) | CNR2CNR1MEN1KMT2AALOX15 | |
| SCHEMBL27293376 | 0.86 | CNR2 (0.55) | CNR2CNR1MEN1KMT2AALOX15 | |
| SCHEMBL3030328 | 0.85 | CNR2 (0.55) | CNR2CNR1MEN1KMT2AALOX15 | |
| SCHEMBL7751114 | 0.83 | KMT2A (0.54) | CNR2CNR1MEN1KMT2AALOX15 | |
| SCHEMBL7755680 | 0.83 | KMT2A (0.54) | CNR2CNR1MEN1KMT2AALOX15 | |
| SCHEMBL7754630 | 0.83 | KMT2A (0.54) | CNR2CNR1MEN1KMT2AALOX15 | |
| SCHEMBL7751086 | 0.83 | KMT2A (0.54) | CNR2CNR1MEN1KMT2AALOX15 | |
| SCHEMBL11674325 | 0.83 | CNR2 (0.51) | CNR2CNR1ALOX15CYP3A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009021590-A1 | TYROSINASE INHIBITORS | MERCK PATENT GMBH (DE) | 2009-02-19 | — | — | WO | claimed |
| WO-2009021590-A1 | TYROSINASE INHIBITORS | MERCK PATENT GMBH (DE) | 2009-02-19 | — | — | WO | disclosed |